Proteomics analysis of the gut–brain axis in a gut microbiota-dysbiosis model of depression

Y Liu, H Wang, S Gui, B Zeng, J Pu, P Zheng… - Translational …, 2021 - nature.com
Major depressive disorder (MDD) is a serious mental illness. Increasing evidence from both
animal and human studies suggested that the gut microbiota might be involved in the onset …

Gut microbiota regulates depression-like behavior in rats through the neuroendocrine-immune-mitochondrial pathway

S Liu, R Guo, F Liu, Q Yuan, Y Yu… - … disease and treatment, 2020 - Taylor & Francis
Purpose Gut microbiota affects various physiological functions in the host and has crucial
effects on the nervous system. There is increasing evidence of a correlation between gut …

[HTML][HTML] Multi-omics data reveals the disturbance of glycerophospholipid metabolism caused by disordered gut microbiota in depressed mice

T Tian, Q Mao, J Xie, Y Wang, W Shao, Q Zhong… - Journal of advanced …, 2022 - Elsevier
Introduction Although researchers have done intensive research on depression, its
pathogenesis is still not fully explained. More and more evidence suggests that gut …

[HTML][HTML] CUMS and dexamethasone induce depression-like phenotypes in mice by differentially altering gut microbiota and triggering macroglia activation

J Wu, J Li, C Gaurav, U Muhammad, Y Chen… - General …, 2021 - ncbi.nlm.nih.gov
Background Although the link between gut microbiota and depression has been suggested,
changes of gut microbiota vary largely among individuals with depression. Aims Explore the …

The microbiota-gut-brain axis in pathogenesis of depression: A narrative review

H Yao, D Zhang, H Yu, H Shen, H Liu, F Meng… - Physiology & …, 2023 - Elsevier
The microbiota-gut-brain axis is a bidirectional regulatory pathway between the brain and
the gastrointestinal tract, which plays an important role in maintain homeostasis. Gut …

The microbiota–gut–brain axis in depression: The potential pathophysiological mechanisms and microbiota combined antidepression effect

F Zhu, H Tu, T Chen - Nutrients, 2022 - mdpi.com
Depression is a kind of worldwide mental illness with the highest morbidity and disability
rate, which is often accompanied by gastrointestinal symptoms. Experiments have …

Gut microbiome remodeling induces depressive-like behaviors through a pathway mediated by the host's metabolism

P Zheng, B Zeng, C Zhou, M Liu, Z Fang, X Xu… - Molecular …, 2016 - nature.com
Major depressive disorder (MDD) is the result of complex gene–environment interactions.
According to the World Health Organization, MDD is the leading cause of disability …

The gut microbiome modulates the changes in liver metabolism and in inflammatory processes in the brain of chronic unpredictable mild stress rats

W Lv, X Wu, W Chen, Y Li, G Zhang… - Oxidative Medicine …, 2019 - Wiley Online Library
Generally, depression is the result of complex gene‐environment interactions. Recent
studies have showed that the gut microbiota can affect brain function through the microbiota …

Altered gut metabolome contributes to depression-like behaviors in rats exposed to chronic unpredictable mild stress

L Jianguo, J Xueyang, W Cui, W Changxin… - Translational …, 2019 - nature.com
The gut microbiota has been increasingly correlated with depressive disorder. It was
recently shown that the transplantation of the gut microbiota from depressed patients to …

Effects of 'healthy'fecal microbiota transplantation against the deterioration of depression in fawn-hooded rats

B Hu, P Das, X Lv, M Shi, J Aa, K Wang, L Duan… - Msystems, 2022 - Am Soc Microbiol
Depression is a recurrent, heterogeneous mood disorder occurring in more than 260 million
people worldwide. Gut microbiome dysbiosis is associated with the development of …