Linking stressful life events and chronic inflammation using suPAR (soluble urokinase plasminogen activator receptor)

KJ Bourassa, LJH Rasmussen, A Danese… - Brain, behavior, and …, 2021 - Elsevier
Stressful life events have been linked to declining health, and inflammation has been
proposed as a physiological mechanism that might explain this association. Using 828 …

Association between elevated suPAR, a new biomarker of inflammation, and accelerated aging

LJH Rasmussen, A Caspi, A Ambler… - The Journals of …, 2021 - academic.oup.com
Background To understand and measure the association between chronic inflammation,
aging, and age-related diseases, broadly applicable standard biomarkers of systemic …

Childhood and later life stressors and increased inflammatory gene expression at older ages

ME Levine, SW Cole, DR Weir, EM Crimmins - Social science & medicine, 2015 - Elsevier
Adverse experiences in early life have the ability to “get under the skin” and affect future
health. This study examined the relative influence of adversities during childhood and …

Cumulative childhood risk is associated with a new measure of chronic inflammation in adulthood

LJH Rasmussen, TE Moffitt… - Journal of Child …, 2019 - Wiley Online Library
Background Childhood risk factors are associated with elevated inflammatory biomarkers in
adulthood, but it is unknown whether these risk factors are associated with increased adult …

Which types of stress are associated with accelerated biological aging? Comparing perceived stress, stressful life events, childhood adversity, and posttraumatic …

KJ Bourassa, A Caspi, GM Brennan… - Psychosomatic …, 2023 - journals.lww.com
Objective Stress and stressful events are associated with poorer health; however, there are
multiple ways to conceptualize and measure stress and stress responses. One physiological …

Associations of lifetime trauma and chronic stress with C-reactive protein in adults ages 50 years and older: examining the moderating role of perceived control

AJ Elliot, CJ Mooney, FJ Infurna… - Psychosomatic …, 2017 - journals.lww.com
Objective The aim of the study was to investigate whether high perceived control mitigates
systemic inflammatory risk associated with traumatic and chronic stress exposures in older …

Early-life stress, depressive symptoms, and inflammation: The role of social factors

JS Nakamura, ES Kim, KE Rentscher… - Aging & mental …, 2022 - Taylor & Francis
Objective To identify modifiable, social factors that moderate the relationship between early-
life stress (ELS) and health outcomes as measured by depressive symptoms and …

Association of adverse experiences and exposure to violence in childhood and adolescence with inflammatory burden in young people

LJH Rasmussen, TE Moffitt, L Arseneault… - JAMA …, 2020 - jamanetwork.com
Importance Childhood stress exposure is associated with inflammation as measured by C-
reactive protein (CRP) and interleukin 6 (IL-6). However, findings are inconsistent and effect …

Perceived stress is linked to heightened biomarkers of inflammation via diurnal cortisol in a national sample of adults

EL Knight, Y Jiang, J Rodriguez-Stanley… - Brain, Behavior, and …, 2021 - Elsevier
Exposure to and perceptions of stress have been associated with altered systemic
inflammation, but the intermediate processes by which stress links to inflammation are not …

Response and habituation of pro-and anti-inflammatory gene expression to repeated acute stress

CM McInnis, D Wang, D Gianferante, L Hanlin… - Brain, behavior, and …, 2015 - Elsevier
Introduction Acute stress induces increases in plasma inflammatory mediators, which do not
habituate to repeated stress. Inflammation is a risk factor for age-related illnesses …