Cytokines are responsible for maintaining homeostasis as cell growth, differentiation,
migration and apoptosis mediators. They play a pivotal role in immune responses to …

The idea of a potential link between cancer and inflammation was first proposed by R.
Virchow in the nineteenth century. However, clear evidence regarding a key role of …

Interleukin (IL)-13 has been reported to have a role in the pathogenesis of lymphoma
through recent molecular studies predominantly in adult patients. As malignant lymphomas …

Abstract IL‐23 is an IL‐12 cytokine family member with pleiotropic functions that regulates
tumour growth in various cancer types, exhibiting both anti‐tumorigenic and pro‐tumorigenic …

Interleukin-6 (IL-6) is proinflammatory cytokine that produces multifunctional effects. It is also
involved in the regulation of immune reactions, hematopoiesis and inflammatory state …

Abstract BACKGROUND Interleukin (IL)‐6 plays a central role as a differentiation and
growth factor of tumor cells. It may be hypothesized that increased serum IL‐6 derives from …

OBJECTIVES: Deregulated serum IL-10, IL-12 and their reciprocal balance have been
stated in malignancies of adults. In children with cancer the issue has not been investigated …

Purpose The study investigated interleukin-6 expression pattern across all stages of cancer.
The research questions raised in the study were: Is there differential expression of …

Blood levels of the immunosuppressive cytokines IL-6 and IL-10 are often abnormally high
in patients with advanced cancer. However, since IL-6 and IL-10 may be produced by …

The study aimed at analysis of tissue expression of interleukin 2 (IL-2) and subunit α of its
receptor (IL-2Rα/CD25) in B-cell non-Hodgkin lymphomas (B-cell NHLs) in children as …