Perioperative cardioprotection: general mechanisms and pharmacological approaches

C Torregroza, A Raupach, K Feige… - Anesthesia & …, 2020 - journals.lww.com
Cardioprotection encompasses a variety of strategies protecting the heart against
myocardial injury that occurs during and after inadequate blood supply to the heart during …

Perioperative cardioprotection: clinical implications

S Roth, C Torregroza, R Huhn… - Anesthesia & …, 2020 - journals.lww.com
Perioperative cardioprotection aims to minimize the consequences of myocardial ischemia–
reperfusion injury. In isolated tissue and animal experiments, several treatments have been …

Pharmacological conditioning of the heart: an update on experimental developments and clinical implications

S Roth, C Torregroza, K Feige, B Preckel… - International journal of …, 2021 - mdpi.com
The aim of pharmacological conditioning is to protect the heart against myocardial ischemia-
reperfusion (I/R) injury and its consequences. There is extensive literature that reports a …

Adjuvant cardioprotection in cardiac surgery: update

R Wagner, P Piler, Z Gabbasov… - BioMed Research …, 2014 - Wiley Online Library
Cardiac surgery patients are now more risky in terms of age, comorbidities, and the need for
complex procedures. It brings about reperfusion injury, which leads to dysfunction and/or …

Cardioprotection in anesthesia.

SG De Hert - Minerva anestesiologica, 2008 - europepmc.org
Ischemic heart disease is the major cause of morbidity and mortality in the Western world.
With the advancing age of the surgical population, anesthesiologists increasingly have to …

The concept of anaesthetic-induced cardioprotection: mechanisms of action

NC Weber, W Schlack - Best Practice & Research Clinical Anaesthesiology, 2005 - Elsevier
The mechanisms by which ischaemia reperfusion injury can be influenced have been the
subject of extensive research in the last decades. Early restoration of arterial blood flow and …

Perioperative cardioprotection: back to bedside.

V Lionetti, L Barile - Minerva anestesiologica, 2019 - europepmc.org
A comment on this article appears in" Back and forth from basic science to clinical
translation." Minerva Anestesiol. 2020 Aug; 86 (8): 890-891. A comment on this article …

'Conditioning'the heart during surgery

V Venugopal, A Ludman, DM Yellon… - European journal of …, 2009 - academic.oup.com
Coronary heart disease (CHD) is the leading cause of death worldwide. Coronary artery
bypass graft (CABG) surgery remains the procedure of choice for coronary artery …

Peri‐operative anaesthetic myocardial preconditioning and protection–cellular mechanisms and clinical relevance in cardiac anaesthesia

G Kunst, AA Klein - Anaesthesia, 2015 - Wiley Online Library
Preconditioning has been shown to reduce myocardial damage caused by ischaemia–
reperfusion injury peri‐operatively. Volatile anaesthetic agents have the potential to provide …

Anesthetic preconditioning: have we found the holy grail of perioperative cardioprotection?

S De Hert, A Moerman - Journal of Cardiothoracic and Vascular …, 2018 - jcvaonline.com
SINCE THE MID-1970s, one of the important topics of anesthesiological research has been
the exploration of potential beneficial effects of anesthetics agents, and more specifically the …