Heterogeneous fluid-like movements of chromatin and their implications to transcription
SS Ashwin, K Maeshima, M Sasai - Biophysical Reviews, 2020 - Springer
Eukaryotic chromatin is a complex of genome DNA and associated proteins, and its structure
and dynamics play a crucial role in regulating DNA functions. Chromatin takes rather …
and dynamics play a crucial role in regulating DNA functions. Chromatin takes rather …
Local chromatin motion and transcription
Eukaryotic chromatin is a complex of nucleic acids and proteins that is central to interpreting
the information coded in the genome. Chromatin is rather irregularly folded inside the …
the information coded in the genome. Chromatin is rather irregularly folded inside the …
Spatial organization of chromosomes leads to heterogeneous chromatin motion and drives the liquid-or gel-like dynamical behavior of chromatin
Chromosome organization and dynamics are involved in regulating many fundamental
processes such as gene transcription and DNA repair. Experiments unveiled that chromatin …
processes such as gene transcription and DNA repair. Experiments unveiled that chromatin …
Organization of fast and slow chromatin revealed by single-nucleosome dynamics
Understanding chromatin organization and dynamics is important, since they crucially affect
DNA functions. In this study, we investigate chromatin dynamics by statistically analyzing …
DNA functions. In this study, we investigate chromatin dynamics by statistically analyzing …
Chromatin dynamics in living cells: identification of oscillatory motion
A Pliss, KS Malyavantham… - Journal of cellular …, 2013 - Wiley Online Library
Genomic DNA in mammalian cells is organized into∼ 1 Mbp chromatin domains (ChrD)
which represent the basic structural units for DNA compaction, replication, and transcription …
which represent the basic structural units for DNA compaction, replication, and transcription …
Micron-scale coherence in interphase chromatin dynamics
A Zidovska, DA Weitz… - Proceedings of the …, 2013 - National Acad Sciences
Chromatin structure and dynamics control all aspects of DNA biology yet are poorly
understood, especially at large length scales. We developed an approach, displacement …
understood, especially at large length scales. We developed an approach, displacement …
Single-nucleosome imaging reveals steady-state motion of interphase chromatin in living human cells
Dynamic chromatin behavior plays a critical role in various genome functions. However, it
remains unclear how chromatin behavior changes during interphase, where the nucleus …
remains unclear how chromatin behavior changes during interphase, where the nucleus …
[HTML][HTML] Effects of transcription-dependent physical perturbations on the chromosome dynamics in living cells
H Ku, G Park, J Goo, J Lee, TL Park, H Shim… - Frontiers in Cell and …, 2022 - frontiersin.org
Recent studies with single-particle tracking in live cells have revealed that chromatin
dynamics are directly affected by transcription. However, how transcription alters the …
dynamics are directly affected by transcription. However, how transcription alters the …
[HTML][HTML] Internal motion of chromatin fibers is governed by dynamics of uncompressed linker strands
Chromatin compaction and internal motion are fundamental aspects of gene expression
regulation. Here, we have investigated chromatin fibers comprising recombinant histone …
regulation. Here, we have investigated chromatin fibers comprising recombinant histone …
Chromosome dynamics in response to DNA damage
Recent advances in both the technologies used to measure chromatin movement and the
biophysical analysis used to model them have yielded a fuller understanding of chromatin …
biophysical analysis used to model them have yielded a fuller understanding of chromatin …