High-throughput sequencing (HTS) for the analysis of viral populations

M Pérez-Losada, M Arenas, JC Galán… - Infection, Genetics and …, 2020 - Elsevier
Abstract The development of High-Throughput Sequencing (HTS) technologies is having a
major impact on the genomic analysis of viral populations. Current HTS platforms can …

Bioinformatics tools for analysing viral genomic data

RJ Orton, Q Gu, J Hughes, M Maabar… - Revue scientifique et …, 2016 - eprints.gla.ac.uk
The field of viral genomics and bioinformatics is experiencing a strong resurgence due to
high-throughput sequencing (HTS) technology, which enables the rapid and cost-effective …

[HTML][HTML] Next-generation sequencing technology in clinical virology

MR Capobianchi, E Giombini, G Rozera - Clinical Microbiology and …, 2013 - Elsevier
Recent advances in nucleic acid sequencing technologies, referred to as 'next-generation'
sequencing (NGS), have produced a true revolution and opened new perspectives for …

[HTML][HTML] Considerations for optimization of high-throughput sequencing bioinformatics pipelines for virus detection

C Lambert, C Braxton, RL Charlebois, A Deyati… - Viruses, 2018 - mdpi.com
High-throughput sequencing (HTS) has demonstrated capabilities for broad virus detection
based upon discovery of known and novel viruses in a variety of samples, including clinical …

Genomic analysis of viral outbreaks

S Wohl, SF Schaffner, PC Sabeti - Annual review of virology, 2016 - annualreviews.org
Genomic analysis is a powerful tool for understanding viral disease outbreaks. Sequencing
of viral samples is now easier and cheaper than ever before and can supplement …

[HTML][HTML] Current trends in diagnostics of viral infections of unknown etiology

D Kiselev, A Matsvay, I Abramov, V Dedkov, G Shipulin… - Viruses, 2020 - mdpi.com
Viruses are evolving at an alarming rate, spreading and inconspicuously adapting to cutting-
edge therapies. Therefore, the search for rapid, informative and reliable diagnostic methods …

[HTML][HTML] Application of next-generation sequencing technologies in virology

AD Radford, D Chapman, L Dixon… - Journal of General …, 2012 - microbiologyresearch.org
The progress of science is punctuated by the advent of revolutionary technologies that
provide new ways and scales to formulate scientific questions and advance knowledge …

Metagenomic identification of viral pathogens

K Bibby - Trends in biotechnology, 2013 - cell.com
The target-independent identification of viral pathogens using 'shotgun'metagenomic
sequencing is an emerging approach with potentially wide applications in clinical …

Comparing viral metagenomics methods using a highly multiplexed human viral pathogens reagent

L Li, X Deng, ET Mee, S Collot-Teixeira… - Journal of virological …, 2015 - Elsevier
Unbiased metagenomic sequencing holds significant potential as a diagnostic tool for the
simultaneous detection of any previously genetically described viral nucleic acids in clinical …

[HTML][HTML] Virus classification–where do you draw the line?

P Simmonds, P Aiewsakun - Archives of virology, 2018 - Springer
High-throughput sequencing (HTS) and its use in recovering and assembling novel virus
sequences from environmental, human clinical, veterinary and plant samples has unearthed …