Consensus gene co-expression network analysis identifies novel genes associated with severity of fibrotic lung disease
Idiopathic pulmonary fibrosis (IPF) is a severe fibrotic lung disease characterized by
irreversible scarring of the lung parenchyma leading to dyspnea, progressive decline in lung …
irreversible scarring of the lung parenchyma leading to dyspnea, progressive decline in lung …
Gene correlation network analysis to identify regulatory factors in idiopathic pulmonary fibrosis
Background Idiopathic pulmonary fibrosis (IPF) is a severe lung disease characterised by
extensive pathological changes. The objective for this study was to identify the gene network …
extensive pathological changes. The objective for this study was to identify the gene network …
Integrative analysis of transcriptome-wide association study and mRNA expression profiles identifies candidate genes associated with idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a type of scarring lung disease characterized by a
chronic, progressive, and irreversible decline in lung function. The genetic basis of IPF …
chronic, progressive, and irreversible decline in lung function. The genetic basis of IPF …
Integrative analysis of lung molecular signatures reveals key drivers of idiopathic pulmonary fibrosis
SK Kim, SM Jung, KS Park, KJ Kim - BMC Pulmonary Medicine, 2021 - Springer
Background Idiopathic pulmonary fibrosis (IPF) is a devastating disease with a high clinical
burden. The molecular signatures of IPF were analyzed to distinguish molecular subgroups …
burden. The molecular signatures of IPF were analyzed to distinguish molecular subgroups …
Identification of key modules and hub genes associated with lung function in idiopathic pulmonary fibrosis
Y Xia, C Lei, D Yang, H Luo - PeerJ, 2020 - peerj.com
Background Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive interstitial lung
disease, characterized by a decline in lung function. To date, the pathophysiologic …
disease, characterized by a decline in lung function. To date, the pathophysiologic …
BAL transcriptomes characterize idiopathic pulmonary fibrosis endotypes with prognostic impact
LJ De Sadeleer, SE Verleden, JC Schupp… - Chest, 2022 - Elsevier
Background Given the plethora of pathophysiologic mechanisms described in idiopathic
pulmonary fibrosis (IPF), we hypothesize that the mechanisms driving fibrosis in IPF may be …
pulmonary fibrosis (IPF), we hypothesize that the mechanisms driving fibrosis in IPF may be …
Identification of key candidate genes involved in the progression of idiopathic pulmonary fibrosis
Y Cui, J Ji, J Hou, Y Tan, X Han - Molecules, 2021 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is a lethal, agnogenic interstitial lung disease with limited
therapeutic options. To investigate vital genes involved in the development of IPF, we …
therapeutic options. To investigate vital genes involved in the development of IPF, we …
[HTML][HTML] Identification of transcriptomic markers for developing idiopathic pulmonary fibrosis: an integrative analysis of gene expression profiles
D Li, Y Liu, B Wang - International Journal of Clinical and …, 2020 - ncbi.nlm.nih.gov
Idiopathic pulmonary fibrosis (IPF) remains a lethal disease with unknown etiology and
unmet medical need. The aim of this study was to perform an integrative analysis of multiple …
unmet medical need. The aim of this study was to perform an integrative analysis of multiple …
Detecting the molecular system signatures of idiopathic pulmonary fibrosis through integrated genomic analysis
I Gangwar, N Kumar Sharma, G Panzade, S Awasthi… - Scientific reports, 2017 - nature.com
Abstract Idiopathic Pulmonary Fibrosis (IPF) is an incurable progressive fibrotic disease of
the lungs. We currently lack a systematic understanding of IPF biology and a systems …
the lungs. We currently lack a systematic understanding of IPF biology and a systems …
Identification and validation of potential biomarkers and pathways for idiopathic pulmonary fibrosis by comprehensive bioinformatics analysis
W Qian, X Cai, Q Qian, X Zhang - BioMed research …, 2021 - Wiley Online Library
Objective. Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, irreversible, high‐
mortality lung disease, but its pathogenesis is still unclear. Our purpose was to explore …
mortality lung disease, but its pathogenesis is still unclear. Our purpose was to explore …