[HTML][HTML] Time moderates the interplay between 5-HTTLPR and stress on depression risk: gene x environment interaction as a dynamic process
C Delli Colli, M Borgi, S Poggini, F Chiarotti… - Translational …, 2022 - nature.com
The serotonin-transporter-linked promoter region (5-HTTLPR) has been widely investigated
as contributing to depression vulnerability. Nevertheless, empirical research provides wide …
as contributing to depression vulnerability. Nevertheless, empirical research provides wide …
Current developments and controversies: does the serotonin transporter gene-linked polymorphic region (5-HTTLPR) modulate the association between stress and …
M Wankerl, S Wüst, C Otte - Current Opinion in Psychiatry, 2010 - journals.lww.com
Whereas there is no doubt that the meta-analyses are methodologically sound, it appears
that this technique is only in part suitable for appraising all of the available evidence …
that this technique is only in part suitable for appraising all of the available evidence …
[HTML][HTML] Protocol for a collaborative meta-analysis of 5-HTTLPR, stress, and depression
Background Debate is ongoing about what role, if any, variation in the serotonin transporter
linked polymorphic region (5-HTTLPR) plays in depression. Some studies report an …
linked polymorphic region (5-HTTLPR) plays in depression. Some studies report an …
Gene-environment interactions between stress and 5-HTTLPR in depression: A meta-analytic update
Background Meta-analyses have yielded contradictory findings concerning the role of 5-
HTTLPR in interaction with stress (GxE) in depression. The current meta-analysis …
HTTLPR in interaction with stress (GxE) in depression. The current meta-analysis …
An update on the interaction between the serotonin transporter promoter variant (5-HTTLPR), stress and depression, plus an exploration of non-confirming findings
CF Sharpley, SKA Palanisamy, NS Glyde… - Behavioural brain …, 2014 - Elsevier
In the three years since the most recent meta-analysis of the association between the
serotonin transported promoter polymorphism (5-HTTLPR), stress and the development of …
serotonin transported promoter polymorphism (5-HTTLPR), stress and the development of …
Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression
RC Culverhouse, NL Saccone, AC Horton, Y Ma… - Molecular …, 2018 - nature.com
The hypothesis that the S allele of the 5-HTTLPR serotonin transporter promoter region is
associated with increased risk of depression, but only in individuals exposed to stressful …
associated with increased risk of depression, but only in individuals exposed to stressful …
The serotonin transporter promoter variant (5-HTTLPR), stress, and depression meta-analysis revisited: evidence of genetic moderation
K Karg, M Burmeister, K Shedden… - Archives of general …, 2011 - jamanetwork.com
Objective: To perform a meta-analysis including all relevant studies exploring the interaction.
Data Sources: We identified studies published through November 2009 in PubMed. Study …
Data Sources: We identified studies published through November 2009 in PubMed. Study …
[HTML][HTML] Daily stress reactivity and serotonin transporter gene (5-HTTLPR) variation: Internalizing responses to everyday stress as a possible transdiagnostic …
CC Conway, GM Slavich, C Hammen - Biology of mood & anxiety …, 2014 - Springer
Background Recent studies examining the interaction between the 5-HTTLPR locus in the
serotonin transporter gene and life stress in predicting depression have yielded equivocal …
serotonin transporter gene and life stress in predicting depression have yielded equivocal …
The involvement of sleep in the relationship between the serotonin transporter gene-linked polymorphic region (5-HTTLPR) and depression: a systematic review
JH van Dalfsen, CR Markus - Journal of Affective Disorders, 2019 - Elsevier
Background Recent meta-analyses stimulate an ongoing debate whether 5-HTTLPR
modulates the risk for depression including a more pronounced association between stress …
modulates the risk for depression including a more pronounced association between stress …
Update on the 2005 paper: moderation of mental and physical distress by polymorphisms in the 5-HT transporter gene by interacting with social stressors and chronic …
HJ Grabe, C Schwahn, K Appel, J Mahler… - Molecular …, 2011 - nature.com
There is a controversial and ongoing debate on whether mental distress is moderated by an
interaction between the insertion or deletion promoter polymorphism of the serotonin …
interaction between the insertion or deletion promoter polymorphism of the serotonin …