As the global population becomes older, understanding the impact of aging on health and
disease becomes paramount. Recent advancements in multiomic technology have allowed …

Metabolomics is the latest 'omics' technology and systems biology science that allows for
comprehensive profiling of small-molecule metabolites in biological systems at a specific …

Metabolomics is the latest state-of-the-art omics technology that provides a comprehensive
quantitative profile of metabolites. The metabolites are the cellular end products of metabolic …

Diversity is observed in the wave of global aging because it is a complex biological process
exhibiting individual variability. To assess aging physiologically, markers for biological aging …

Mass spectrometry‐based metabolomics has emerged as a powerful technique for
biomedical research, although technical issues with its analytical precision and structural …

Understanding how metabolites are longitudinally influenced by age and sex could facilitate
the identification of metabolomic profiles and trajectories that indicate disease risk. We …

Understanding the complexity of aging is of utmost importance. This can now be addressed
by the novel and powerful approach of metabolomics. However, to date, only a few …

Chronological age is an important predictor of morbidity and mortality; however, it is unable
to account for heterogeneity in the decline of physiological function and health with …

The dysregulation of cellular metabolism is a hallmark of ageing. To understand the
metabolic changes that occur as a consequence of the ageing process and to find …

A molecular description of the mechanisms by which aging is produced is still very limited.
Here, we have determined the plasma metabolite profile by using high-throughput …