Objective Peroxisome proliferator-activated receptors (PPARs) are key transcription factors
that regulate adipose development and function, and the conversion of white into brown-like …

A better understanding of the mechanisms underlying obesity and its comorbidities is key to
designing new therapies and treatments. PPARγ is a master regulator of adipocyte biology …

High expression of the peroxisome proliferator-activated receptor α (PPARα) differentiates
brown fat from white, and is related to its high capacity of lipid oxidation. We analyzed the …

The potential role of brown and beige adipose tissue against obesity has been recognized.
Browning, or beiging of white adipose tissue (WAT) is associated with the remodeling of …

Peroxisome proliferator-activated receptors (PPARs) have been suggested as the master
regulators of adipose tissue formation. However, their role in regulating brown fat …

The presence of brown adipose tissue (BAT) in human adults opens attractive perspectives
to treat metabolic disorders. Indeed, BAT dissipates energy as heat via uncoupling protein …

Mice with a dominant-negative peroxisome proliferator-activated receptor γ (PPARγ)
mutation (P465L) unexpectedly had normal amounts of adipose tissue. Here, we investigate …

Peroxisome proliferator activated receptor α (PPARα) is a distinctive marker of the brown fat
phenotype that has been proposed to coordinate the transcriptional activation of genes for …

Obesity is considered a public health problem worldwide. Fenofibrate, a selective
peroxisome proliferator‐activated receptor α (PPAR‐α) agonist, elicits weight loss in animal …

Objectives To examine the effects of a selective peroxisome proliferator-activated receptor
(PPAR-α) agonist treatment on interscapular brown adipose tissue (iBAT) whitening …