Gutted! Unraveling the role of the microbiome in major depressive disorder

TFS Bastiaanssen, S Cussotto… - Harvard Review of …, 2020 - journals.lww.com
Microorganisms can be found in virtually any environment. In humans, the largest collection
of microorganisms is found in the gut ecosystem. The adult gut microbiome consists of more …

How microbes affect depression: underlying mechanisms via the Gut–brain axis and the modulating role of probiotics

K Suda, K Matsuda - International journal of molecular sciences, 2022 - mdpi.com
Accumulating evidence suggests that the gut microbiome influences the brain functions and
psychological state of its host via the gut–brain axis, and gut dysbiosis has been linked to …

Gut microbiota composition in depressive disorder: a systematic review, meta-analysis, and meta-regression

M Gao, J Wang, P Liu, H Tu, R Zhang, Y Zhang… - Translational …, 2023 - nature.com
Studies investigating gut microbiota composition in depressive disorder have yielded mixed
results. The aim of our study was to compare gut microbiome between people with …

The gut microbiome in human health and disease—Where are we and where are we going? A bibliometric analysis

Z Huang, K Liu, W Ma, D Li, T Mo, Q Liu - Frontiers in Microbiology, 2022 - frontiersin.org
Background There are trillions of microbiota in our intestinal tract, and they play a significant
role in health and disease via interacting with the host in metabolic, immune, neural, and …

Current understanding of gut microbiota in mood disorders: an update of human studies

TT Huang, JB Lai, YL Du, Y Xu, LM Ruan… - Frontiers in genetics, 2019 - frontiersin.org
Gut microbiota plays an important role in the bidirectional communication between the gut
and the central nervous system. Mounting evidence suggests that gut microbiota can …

[HTML][HTML] “I am I and my bacterial circumstances”: linking gut microbiome, neurodevelopment, and depression

JM Lima-Ojeda, R Rupprecht, TC Baghai - Frontiers in psychiatry, 2017 - frontiersin.org
Recently, there has been renewed interest in the role played by microbiome in both human
health and human disease. A correct equilibrium between the human host and their …

[HTML][HTML] Gut microbiota and pathophysiology of depressive disorder

H Kunugi - Annals of Nutrition and Metabolism, 2021 - karger.com
Background: Accumulating evidence has suggested that the bi-directional communication
pathway, the microbiota-gut-brain axis, plays an important role in the pathophysiology of …

The role of inflammation and the gut microbiome in depression and anxiety

JM Peirce, K Alviña - Journal of neuroscience research, 2019 - Wiley Online Library
The study of the gut microbiome has increasingly revealed an important role in modulating
brain function and mental health. In this review, we underscore specific pathways and …

Gut emotions-mechanisms of action of probiotics as novel therapeutic targets for depression and anxiety disorders

A Slyepchenko, AF Carvalho, DS Cha… - CNS & Neurological …, 2014 - ingentaconnect.com
A priority clinical and research agenda in mood and anxiety disorders is to identify
determinants that influence illness trajectory and outcome. Over the past decade, studies …

Multi-cohort analysis of depression-associated gut bacteria sheds insight on bacterial biomarkers across populations

S Liang, ZY Sin, J Yu, S Zhao, Z Xi, R Bruzzone… - Cellular and Molecular …, 2023 - Springer
Gut microbes are associated with the development of depression based on extensive
evidence. However, previous studies have led to conflicting reports on this association …