The origins of modern psychology are deeply rooted in the notion that stressful early-life
experiences negatively impact people's mental health. Emerging work in the field of health …

Early-life stress is associated with increased vulnerability to physical and emotional health
problems across the lifespan. The recently developed neuroimmune network hypothesis …

Early life stressors are associated with elevated inflammation, a key physiological risk factor
for disease. However, the mechanisms by which early stress leads to inflammation remain …

There is considerable evidence that stressful early life events influence a variety of physical
health problems later in life. Childhood adversity has been linked to elevated rates of …

Research relating stress to health has progressed from anecdotal evidence in the 1930s
and 1940s to complex multivariate models that identify underlying longitudinal mechanisms …

Repeated maternal separation is the most widely used pre-clinical approach to investigate
the relationship between early-life chronic stress and its neuropsychiatric and physical …

There is now reliable evidence that early psychosocial stress exposures are associated with
behavioral health in children; the degree to which these same kinds of stress exposures …

Psychological stress during childhood and adolescence increases risk of health problems
across the lifecourse, and inflammation is implicated as an underlying mechanism. To …

Background Early life stress (ELS) has been linked to health disparities across the human
lifespan, particularly increased risk for depression and its recurrence. In this study we …

Adverse experiences in early life have the ability to “get under the skin” and affect future
health. This study examined the relative influence of adversities during childhood and …