Stress in early life has been associated with insufficient glucocorticoid signaling in
adulthood, possibly affecting inflammation processes. Childhood maltreatment has been …

Background Children exposed to social adversity carry a greater risk of poor physical and
mental health into adulthood. This increased risk is thought to be due, in part, to …

BACKGROUND: Retrospective studies show that childhood adversity is associated with
systemic inflammation in adulthood. Few prospective studies have examined whether …

Prior research has found inconsistent evidence regarding the association among childhood
adversity, inflammation, and internalizing symptoms, perhaps because previous studies …

Objective Childhood victimization is an important risk factor for later immune-related
disorders. Previous evidence has demonstrated that childhood victimization is associated …

Early life stressors are associated with elevated inflammation, a key physiological risk factor
for disease. However, the mechanisms by which early stress leads to inflammation remain …

Background The relationship between adverse childhood experiences (ACE) and poorer
health across the life course is well established. Increased chronic inflammation might be …

Childhood maltreatment represents a significant risk factor for the development of a number
of mental and physical health outcomes. Converging evidence suggests that early adversity …

Background Childhood abuse leads to greater morbidity and mortality in adulthood.
Dysregulated physiological stress responses may underlie the greater health risk among …

Introduction Child maltreatment (CM) is associated with mental and physical health
disorders in adulthood. Some studies have identified elevated markers of systemic …