Colorectal cancer prediction based on weighted gene co-expression network analysis and variational auto-encoder

D Ai, Y Wang, X Li, H Pan - Biomolecules, 2020 - mdpi.com
An effective feature extraction method is key to improving the accuracy of a prediction model.
From the Gene Expression Omnibus (GEO) database, which includes 13,487 genes, we …

[Retracted] Identification of 9 Gene Signatures by WGCNA to Predict Prognosis for Colon Adenocarcinoma

M Yang, H He, T Peng, Y Lu, J Yu - Computational Intelligence …, 2022 - Wiley Online Library
Background. A risk assessment model for prognostic prediction of colon adenocarcinoma
(COAD) was established based on weighted gene co‐expression network analysis …

Filtered selection coupled with support vector machines generate a functionally relevant prediction model for colorectal cancer

MN Gabere, MA Hussein, MA Aziz - OncoTargets and therapy, 2016 - Taylor & Francis
Purpose There has been considerable interest in using whole-genome expression profiles
for the classification of colorectal cancer (CRC). The selection of important features is a …

Identification of key genes in colorectal cancer diagnosis by weighted gene co-expression network analysis

M Mortezapour, L Tapak, F Bahreini, R Najafi… - Computers in Biology …, 2023 - Elsevier
Background The purpose of this study was using bioinformatics tools to identify biomarkers
and molecular factors involved in the diagnosis of colorectal cancer, which are effective for …

Incorporating gene co-expression network in identification of cancer prognosis markers

S Ma, M Shi, Y Li, D Yi, BC Shia - BMC bioinformatics, 2010 - Springer
Background Extensive biomedical studies have shown that clinical and environmental risk
factors may not have sufficient predictive power for cancer prognosis. The development of …

Discovery of core genes in colorectal cancer by weighted gene co‑expression network analysis

C Liao, X Huang, Y Gong, Q Lin - Oncology letters, 2019 - spandidos-publications.com
The aim of the present study was to investigate the interactions among messenger RNAs
(mRNAs), microRNAs (miRNAs), and long noncoding RNAs (lncRNAs) in colorectal cancer …

Identification of diagnostic biomarkers via weighted correlation network analysis in colorectal cancer using a system biology approach

S Ghafouri-Fard, A Safarzadeh, M Taheri, E Jamali - Scientific Reports, 2023 - nature.com
Colorectal cancer (CRC) is the third most frequent cancer to be diagnosed in both females
and males necessitating identification of effective biomarkers. An in-silico system biology …

[HTML][HTML] Identification of potential biomarkers with colorectal cancer based on bioinformatics analysis and machine learning

A Hammad, M Elshaer, X Tang - Mathematical Biosciences and …, 2021 - aimspress.com
Colorectal cancer (CRC) is one of the most common malignancies worldwide. Biomarker
discovery is critical to improve CRC diagnosis, however, machine learning offers a new …

[HTML][HTML] Prediction and validation of GUCA2B as the hub-gene in colorectal cancer based on co-expression network analysis: In-silico and in-vivo study

S Nomiri, R Hoshyar, E Chamani, Z Rezaei… - Biomedicine & …, 2022 - Elsevier
Background Several serious attempts to treat colorectal cancer have been made in recent
decades. However, no effective treatment has yet been discovered due to the complexities …

Local augmented graph neural network for multi-omics cancer prognosis prediction and analysis

Y Zhang, S Xiong, Z Wang, Y Liu, H Luo, B Li, Q Zou - Methods, 2023 - Elsevier
Cancer prognosis prediction and analysis can help patients understand expected life and
help clinicians provide correct therapeutic guidance. Thanks to the development of …