The phagocytic function of macrophage-enforcing innate immunity and tissue homeostasis

D Hirayama, T Iida, H Nakase - International journal of molecular sciences, 2017 - mdpi.com
Macrophages are effector cells of the innate immune system that phagocytose bacteria and
secrete both pro-inflammatory and antimicrobial mediators. In addition, macrophages play …

Cytokines and macrophages

JM Cavaillon - Biomedicine & pharmacotherapy, 1994 - Elsevier
Macrophages, within the cytokine network, are a major source of many cytokines involved in
immune response, hematopoiesis, inflammation and many other homeostatic processes …

Historical insights into cytokines

CA Dinarello - European journal of immunology, 2007 - Wiley Online Library
Cytokines affect nearly every biological process; these include embryonic development,
disease pathogenesis, non‐specific response to infection, specific response to antigen …

Cytokines and related receptor-mediated signaling pathways

JJ Haddad - Biochemical and biophysical research communications, 2002 - Elsevier
Cytokines represent a multi-diverse family of polypeptide regulators; they are of relatively
low molecular weight, pharmacologically active proteins that are secreted by one cell for the …

[PDF][PDF] Insight into the mechanisms regulating immune homeostasis in health and disease

S Sirisinha - Asian Pacific Journal of Allergy and Immunology, 2011 - apjai-journal.org
Innate and adaptive immune systems consist of cells and molecules that work together in
concert to fight against microbial infection and maintain homeostasis. Hosts encounter …

Regulation of myelopoiesis by proinflammatory cytokines in infectious diseases

Y Chiba, I Mizoguchi, H Hasegawa, M Ohashi… - Cellular and molecular …, 2018 - Springer
Hematopoiesis is hierarchically orchestrated by a very small population of hematopoietic
stem cells (HSCs) that reside in the bone-marrow niche and are tightly regulated to maintain …

An overview of inflammation: mechanism and consequences

AU Ahmed - Frontiers in Biology, 2011 - Springer
Inflammation is an essential response provided by the immune systems that ensures the
survival during infection and tissue injury. Inflammatory responses are essential for the …

Macrophage cytokines: involvement in immunity and infectious diseases

G Arango Duque, A Descoteaux - Frontiers in immunology, 2014 - frontiersin.org
The evolution of macrophages has made them primordial for both development and
immunity. Their functions range from the shaping of body plans to the ingestion and …

Role of SARS-CoV-2-induced cytokine storm in multi-organ failure: Molecular pathways and potential therapeutic options

Y Nazerian, M Ghasemi, Y Yassaghi, A Nazerian… - International …, 2022 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) outbreak has become a global public health
emergency and has led to devastating results. Mounting evidence proposes that the disease …

Controlling cytokine storm is vital in COVID-19

L Tang, Z Yin, Y Hu, H Mei - Frontiers in immunology, 2020 - frontiersin.org
Corona virus disease 2019 (COVID-19) has caused a global outbreak and severely posed
threat to people's health and social stability. Mounting evidence suggests that …