Machine learning approaches and applications in genome wide association study for Alzheimer's disease: A systematic review

AS Alatrany, AJ Hussain, J Mustafina… - IEEE Access, 2022 - ieeexplore.ieee.org
Machine learning algorithms have been used for detection (and possibly) prediction of
Alzheimer's disease using genotype information, with the potential to enhance the outcome …

[PDF][PDF] In-Silico Identification of Single Nucleotide Polymorphisms (SNPs) Associated with Alzheimer's Disease

APM Aljamali - pedia.svuonline.org
Background: With the increase in the aging population, the risk of agerelated conditions
such as AD has also grown. With AD being the most common neurodegenerative disease …

Predicting the disease of Alzheimer (AD) with SNP biomarkers and clinical data based decision support system using data mining classification approaches

O Erdoğan - 2012 - open.metu.edu.tr
Single Nucleotide Polymorphisms (SNPs) are the most common DNA sequence variations
where only a single nucleotide (A, T, C, G) in the human genome differs between …

Developing an early predictive system for identifying genetic biomarkers associated to Alzheimer's disease using machine learning techniques

MM Abd El Hamid, MS Mabrouk… - … : Applications, Basis and …, 2019 - World Scientific
Alzheimer's disease (AD) is an irreversible, progressive disorder that assaults the nerve
cells of the brain. It is the most widely recognized kind of dementia among older adults …

Identification of Alzheimer's disease-related genes based on data integration method

Y Hu, T Zhao, T Zang, Y Zhang, L Cheng - Frontiers in genetics, 2019 - frontiersin.org
Alzheimer disease (AD) is the fourth major cause of death in the elderly following cancer,
heart disease and cerebrovascular disease. Finding candidate causal genes can help in the …

Prioritization of risk genes for Alzheimer's disease: an analysis framework using spatial and temporal gene expression data in the human brain based on support …

S Wang, X Fang, X Wen, C Yang, Y Yang… - Frontiers in …, 2023 - frontiersin.org
Background: Alzheimer's disease (AD) is a complex disorder, and its risk is influenced by
multiple genetic and environmental factors. In this study, an AD risk gene prediction …

Predicting the disease of Alzheimer with SNP biomarkers and clinical data using data mining classification approach: decision tree

O Erdoğan, Y Aydin Son - e-Health–For Continuity of Care, 2014 - ebooks.iospress.nl
Abstract Single Nucleotide Polymorphisms (SNPs) are the most common genomic variations
where only a single nucleotide differs between individuals. Individual SNPs and SNP …

[HTML][HTML] The application of artificial intelligence in the genetic study of Alzheimer's disease

R Mishra, B Li - Aging and disease, 2020 - ncbi.nlm.nih.gov
Alzheimer's disease (AD) is a neurodegenerative disease in which genetic factors contribute
approximately 70% of etiological effects. Studies have found many significant genetic and …

Polygenic risk scores in Alzheimer's disease: current applications and future directions

E Baker, V Escott-Price - Frontiers in Digital Health, 2020 - frontiersin.org
Genome-wide association studies have identified nearly 40 genome-wide significant single
nucleotide polymorphisms (SNPs) which are associated with Alzheimer's Disease (AD). Due …

In silico identification of new genetic variations as potential risk factors for Alzheimer's disease in a microarray-oriented simulation

RR Lemos, CH Castelletti, JL Lima Filho… - Journal of molecular …, 2009 - Springer
Genomic and proteomic studies of neurodegenerative disorders require complementary
approaches to integrate the massive amount of data generated in high throughput …