Genetic Association of ACE2 rs2285666 Polymorphism With COVID-19 Spatial Distribution in India

A Srivastava, A Bandopadhyay, D Das… - Frontiers in …, 2020 - frontiersin.org
Studies on host-pathogen interaction have identified human ACE2 as a host cell receptor
responsible for mediating infection by coronavirus (COVID-19). Subsequent studies have …

ACE2 polymorphisms as potential players in COVID-19 outcome

AS Khayat, PP de Assumpção, BC Meireles Khayat… - PLoS …, 2020 - journals.plos.org
The clinical condition COVID-19, caused by SARS-CoV-2, was declared a pandemic by the
WHO in March 2020. Currently, there are more than 5 million cases worldwide, and the …

SNPs of ACE1 (rs4343) and ACE2 (rs2285666) genes are linked to SARS-CoV-2 infection but not with the severity of disease

N Alimoradi, M Sharqi, D Firouzabadi, MM Sadeghi… - Virology Journal, 2022 - Springer
COVID-19 and the renin-angiotensin system (RAS) are linked by angiotensin-converting
enzyme 2 (ACE2), a key enzyme in RAS that has been validated as a SARS-CoV-2 receptor …

Polymorphisms in ACE, ACE2, AGTR1 genes and severity of COVID-19 disease

M Sabater Molina, E Nicolas Rocamora, AI Bendicho… - PloS one, 2022 - journals.plos.org
Background Infection by the SARS-Cov-2 virus produces in humans a disease of highly
variable and unpredictable severity. The presence of frequent genetic single nucleotide …

Investigating the ACE2 polymorphisms in COVID‐19 susceptibility: An in silico analysis

N Pouladi, S Abdolahi - Molecular genetics & genomic …, 2021 - Wiley Online Library
Abstract Background Novel coronavirus (SARS‐CoV‐2) became an epidemic disease and
lead to a pneumonia outbreak first in December 2019 in Wuhan, China. The symptoms …

SARS-CoV-2 infections and COVID-19 mortalities strongly correlate with ACE1 I/D genotype

N Yamamoto, Y Ariumi, N Nishida, R Yamamoto… - Gene, 2020 - Elsevier
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) causes coronavirus
disease 2019 (COVID-19). The relentless spread and pathogenicity of the virus have …

The impact of ACE2 polymorphisms on COVID-19 disease: susceptibility, severity, and therapy

F Chen, Y Zhang, X Li, W Li, X Liu… - Frontiers in Cellular and …, 2021 - frontiersin.org
The coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has currently spread worldwide, leading to high morbidity and …

ACE deletion allele is associated with susceptibility to SARS-CoV-2 infection and mortality rate: An epidemiological study in the Asian population

A Pati, H Mahto, S Padhi, AK Panda - Clinica Chimica Acta, 2020 - Elsevier
Background Severe acute respiratory syndrome corona virus-2 (SARS-CoV-2) is believed to
have emerged from Wuhan, China, and spreads over 215 countries worldwide. The spike …

Polymorphisms of ACE (I/D) and ACE2 receptor gene (Rs2106809, Rs2285666) are not related to the clinical course of COVID‐19: A case study

S Karakaş Çelik, G Çakmak Genç… - Journal of Medical …, 2021 - Wiley Online Library
Coronavirus disease 2019 (COVID‐19) is an infectious disease, and the reason behind the
currently ongoing pandemic, caused by severe acute respiratory syndrome coronavirus 2 …

Angiotensin–Converting Enzyme (ACE) 1 Gene Polymorphism and Phenotypic Expression of COVID-19 Symptoms

N Yamamoto, N Nishida, R Yamamoto, T Gojobori… - Genes, 2021 - mdpi.com
The renin–angiotensin–aldosterone system (RAAS) appears to play an important role in
SARS-CoV-2 infection. Polymorphisms within the genes that control this enzymatic system …