Transcriptomic effects of healthspan-promoting dietary interventions: current evidence and future directions

D Wahl, TJ LaRocca - Frontiers in nutrition, 2021 - frontiersin.org
Aging is the greatest risk factor most diseases, including cardiovascular disorders, cancers,
diabetes, and neurodegeneration, but select nutritional interventions may profoundly reduce …

Bioactive nutrients and nutrigenomics in age-related diseases

T Rescigno, L Micolucci, MF Tecce, A Capasso - Molecules, 2017 - mdpi.com
The increased life expectancy and the expansion of the elderly population are stimulating
research into aging. Aging may be viewed as a multifactorial process that results from the …

Nutrition and ageing: knowledge, gaps and research priorities

JC Mathers - Proceedings of the Nutrition Society, 2013 - cambridge.org
Over the past two centuries human life expectancy has increased by nearly 50 years.
Genetic factors account for about one-third of the variation in life expectancy so that most of …

Personalized nutrition and healthy aging

JM Ordovas, S Berciano - Nutrition Reviews, 2020 - academic.oup.com
The human lifespan and quality of life depend on complex interactions among genetic,
environmental, and lifestyle factors. Aging research has been remarkably advanced by the …

Nutrigerontology: why we need a new scientific discipline to develop diets and guidelines to reduce the risk of aging‐related diseases

K Verburgh - Aging Cell, 2015 - Wiley Online Library
Many diets and nutritional advice are circulating, often based on short‐or medium‐term
clinical trials and primary outcomes, like changes in LDL cholesterol or weight. It remains …

Dietary restriction and nutrient balance in aging

J Santos, F Leitão-Correia, MJ Sousa… - Oxidative Medicine and …, 2016 - Wiley Online Library
Dietary regimens that favour reduced calorie intake delay aging and age‐associated
diseases. New evidences revealed that nutritional balance of dietary components without …

Evaluating the beneficial effects of dietary restrictions: A framework for precision nutrigeroscience

KA Wilson, M Chamoli, TA Hilsabeck, M Pandey… - Cell metabolism, 2021 - cell.com
Dietary restriction (DR) has long been viewed as the most robust nongenetic means to
extend lifespan and healthspan. Many aging-associated mechanisms are nutrient …

Dietary regulation in health and disease

Q Wu, ZJ Gao, X Yu, P Wang - Signal Transduction and Targeted …, 2022 - nature.com
Nutriments have been deemed to impact all physiopathologic processes. Recent evidences
in molecular medicine and clinical trials have demonstrated that adequate nutrition …

Healthy aging and dietary patterns

LJ Dominguez, N Veronese, E Baiamonte, M Guarrera… - Nutrients, 2022 - mdpi.com
A number of factors contribute to the complex process of aging, which finally define whether
someone will or not develop age-associated chronic diseases in late life. These …

Dietary supplements and natural products: an update on their clinical effectiveness and molecular mechanisms of action during accelerated biological aging

Y Chen, S Hamidu, X Yang, Y Yan, Q Wang, L Li… - Frontiers in …, 2022 - frontiersin.org
Accelerated biological aging, which involves the gradual decline of organ or tissue functions
and the distortion of physiological processes, underlies several human diseases. Away from …