Microglial homeostatic functions are fundamental to regulate the central nervous system
microenvironment. We use conditional cell-specific gene targeting, RNA-seq profiling, high …

Microglia modulate synaptic activity, essential for context-dependent cognitive performance,
allowing organism-level adaptations to different environmental scenarios. Yet, the microglial …

Microglia, the largest population of brain immune cells, continuously interact with synapses
to maintain brain homeostasis. In this study, we use conditional cell-specific gene targeting …

Microglia, as the brain's foremost immune cells, play a pivotal role in maintaining brain
homeostasis through persistent interactions with their environment. In this study, we …

One of the most extensively studied members of the Ras superfamily of small GTPases,
Rac1 is an intracellular signal transducer that remodels actin and phosphorylation signaling …

The field of neuroimmunology is quickly expanding and as the primary immune cell of the
brain, microglia are truly in the spotlight. In 2023, the number of microglia related articles …

Microglia are the largest myeloid cell population in the brain. During injury, disease, or
inflammation, microglia adopt different functional states primarily involved in restoring brain …

Microglial control of activity‐dependent plasticity and synaptic remodeling in neuronal
networks has been the subject of intense research in the past several years. Although …

The molecular biological mechanisms of Alzheimer's disease (AD) involve disease-
associated cross-talk through many genes and include a loss of normal as well as a gain of …

The effects of repeated stress on cognitive impairment are thought to be mediated, at least in
part, by reductions in the stability of dendritic spines in brain regions critical for proper …