… severely ill patients to reduce pneumonia related mortality. The cytokine storm observed in
COVID-19 … infections from the perspective of a dysregulated cytokine and immune response. …

… of pro-inflammatory cytokines, referred to as cytokine storm. … Cytokine storm is defined
as acute overproduction and … α for treating COVID-19-related infections to manage COVID-19 …

… inflammatory response called cytokine storm. Both local tissue inflammation and the cytokine
storm play a fundamental role in the development of COVID-19-related complications, such …

… COVID-19-related CRS patients exhibited increased plasma levels of IL-2, IL-7, IL-10, G-SCF, …
differ, requiring the use of distinct intervention strategies to treat different diseases [136]. …

… The mean base levels of IL-6 and IFN-γ in the intervention group were significantly higher
than their levels in controls (p < 0.05). The intragroup analysis indicated a significant increase …

… cytokines initiate … cytokines involved. We also discuss the induction, function, downstream
signaling, and existing and potential interventions for targeting these cytokines or related …

… cytokine storm. As this is not exclusive to COVID-19, we can learn much from known
immuno-modulatory interventions, … Similarly, cardio-renal syndrome related to COVID-19 can …

… The severe COVID-19 infection persuaded cytokine storm that has been linked with acute
… Blocking signalling events related to or at the level of cytokine production, such as JAK–…

… Cytokine storm syndrome (CSS) has generally been described as a collection of clinical
manifestations resulting from an overactivated immune system. Cytokine storms … interventions. …

… Interventions targeting single cytokines in sepsis, unfortunately, also have a long history of
failure. Although the term cytokine storm conjures up dramatic imagery and has captured the …