Network failure: Biotechnology firms, clusters and collaborations far from the world superclusters

M Gilding, J Brennecke, V Bunton, D Lusher, PL Molloy… - Research Policy, 2020 - Elsevier
This article traces the trajectory of biotechnology firms, clusters and collaborations in Australia
between 2003 and 2014. Combining descriptive analyses, network visualizations and …

Winner takes all? Tech clusters, population centers, and the spatial transformation of US invention

B Chattergoon, WR Kerr - Research Policy, 2022 - Elsevier
San Francisco (#6) and Boston (#10) are two of the identified tech clusters, and the next
largest is San Diego at #17 in terms of the 1980 population ranking. Our analysis focuses on the …

The effect of high-tech clusters on the productivity of top inventors

E Moretti - American Economic Review, 2021 - aeaweb.org
… firms; the nascent autonomous vehicles cluster in Pittsburgh; and the biotech cluster and
medical devices clusters in San Diego. The San Francisco-Silicon Valley region has the largest …

Discovery of novel biosynthetic gene cluster diversity from a soil metagenomic library

ALR Santana-Pereira, M Sandoval-Powers… - Frontiers in …, 2020 - frontiersin.org
… -ribosomal peptide synthetase (NRPS) cluster, a dramatically improved hit rate … clusters
identified by NGS were distinct from known BGCs in the MIBiG database or those PKS clusters

Social capital and innovation in a life science cluster: the role of proximity and family involvement

T Pucci, M Brumana, T Minola, L Zanni - The Journal of Technology …, 2020 - Springer
clusters. We intend to go beyond the assumption that the social capital of firms located within
a cluster … and the returns to inventive activity: Canadian biotechnology firms 1991–2000. In …

[PDF][PDF] Transforming Southern California into a Clean-Tech Hub

M Hanin, J Henkin, S Rahman - M-RCBG Associate Working Paper …, 2023 - hks.harvard.edu
… Further, the cluster's innovation goals were unique and targeted. When compared to the
US’s other major biotech cluster economy in the San Francisco Bay area, Boston biotech

Vertical inheritance facilitates interspecies diversification in biosynthetic gene clusters and specialized metabolites

AB Chase, D Sweeney, MN Muskat, DG Guillén-Matus… - MBio, 2021 - Am Soc Microbiol
… Here, we examine the evolutionary dynamics governing the distribution of natural product
biosynthetic gene clusters (BGCs) among 118 strains representing all nine currently named …

Machine learning identifies clusters of longitudinal autoantibody profiles predictive of systemic lupus erythematosus disease outcomes

MY Choi, I Chen, AE Clarke, MJ Fritzler… - Annals of the …, 2023 - ard.bmj.com
Cluster robustness was high as the original four clusters presented above and the new clusters
… ) (ARI 0.971, where 1.0 represents identical clustering and 0 represents exact opposite). …

The biotech living and the walking dead

PC Godfrey, GN Allen, D Benson - Nature Biotechnology, 2020 - nature.com
… which firms remained local, which ones moved to an economic cluster (which we defined
as Boston, San Diego, or San Francisco), and which ones moved to other locations. …

Distinct subtypes of polycystic ovary syndrome with novel genetic associations: An unsupervised, phenotypic clustering analysis

M Dapas, FTJ Lin, GN Nadkarni, R Sisk, RS Legro… - PLoS …, 2020 - journals.plos.org
… hierarchical cluster … The clusters were replicated in an independent, ungenotyped cohort
of 263 PCOS cases (median and IQR: age = 28 [24–33], BMI = 35.7 [28.4–42.3]). The clustering