… in antibody therapeutics and vaccines that induce antibodies to severe acute respiratory … coronavirus 2 (SARS-CoV-2). Many potently neutralizing anti-SARS-CoV-2 antibodies target the …
D Li, GD Sempowski, KO Saunders… - Annual review of …, 2022 - annualreviews.org
… vary according to recognition epitopes. Several potent … that have antibody-escape mutations and the potential for antibody-… representative SARS-CoV-2 neutralizing antibodies that have …
Y Chen, X Zhao, H Zhou, H Zhu, S Jiang… - Nature Reviews …, 2023 - nature.com
… Moreover, S309 can broadly neutralize sarbecoviruses, including all currently identified SARS-CoV-2 VOC, as the epitope sequences recognized by S309 are highly conserved among …
… infection of authentic SARS-CoV-2 and recombinant VSV/SARS-CoV-2 viruses. We … SARS-CoV-2 S neutralization escape variants. Mechanistic studies showed that these antibodies …
… to understand the molecular basis for immune recognition of SARS-CoV-2 spike (S) … for SARS-CoV-2 neutralization, we determined the structures of two human monoclonal antibodies …
… Fabs, revealing recognition of both S1 A and RBD epitopes on SARS-CoV-2 … SARS-CoV-2 spike mutations. Overall, our studies structurally define a recurrent anti-SARS-CoV-2 antibody …
… ” antibodies revealed an NTD epitope that is recurrently mutated among emerging SARS-CoV-2 … and other non-RBD plasma antibodies are prevalent and have implications for SARS-…
Q Ye, S Lu, KD Corbett - Frontiers in immunology, 2021 - frontiersin.org
… -domain antibodies that bind the SARS-CoV-2 Nucleocapsid protein with high affinity. Each antibody recognizes a specific folded domain of the protein, with two antibodiesrecognizing …
… antibody-mediated neutralization. Both AZD8895 and AZD1061 have strong neutralizing activity against SARS-CoV-… -encoded antibody features enable recognition of the SARS-CoV-2 …