[HTML][HTML] Recognition of the SARS-CoV-2 receptor binding domain by neutralizing antibodies

M Yuan, H Liu, NC Wu, IA Wilson - Biochemical and biophysical research …, 2021 - Elsevier
… of the antibody response against SARS-CoV-… antibody recognition of the SARS-CoV-2
RBD. Three major epitopes on the RBD are recognized by the currently characterized SARS-CoV-…

[HTML][HTML] Complete mapping of mutations to the SARS-CoV-2 spike receptor-binding domain that escape antibody recognition

AJ Greaney, TN Starr, P Gilchuk, SJ Zost, E Binshtein… - Cell host & …, 2021 - cell.com
… in antibody therapeutics and vaccines that induce antibodies to severe acute respiratory …
coronavirus 2 (SARS-CoV-2). Many potently neutralizing anti-SARS-CoV-2 antibodies target the …

SARS-CoV-2 neutralizing antibodies for COVID-19 prevention and treatment

D Li, GD Sempowski, KO Saunders… - Annual review of …, 2022 - annualreviews.org
… vary according to recognition epitopes. Several potent … that have antibody-escape mutations
and the potential for antibody-… representative SARS-CoV-2 neutralizing antibodies that have …

Broadly neutralizing antibodies to SARS-CoV-2 and other human coronaviruses

Y Chen, X Zhao, H Zhou, H Zhu, S Jiang… - Nature Reviews …, 2023 - nature.com
… Moreover, S309 can broadly neutralize sarbecoviruses, including all currently identified
SARS-CoV-2 VOC, as the epitope sequences recognized by S309 are highly conserved among …

Neutralizing and protective human monoclonal antibodies recognizing the N-terminal domain of the SARS-CoV-2 spike protein

N Suryadevara, S Shrihari, P Gilchuk, LA VanBlargan… - Cell, 2021 - cell.com
… infection of authentic SARS-CoV-2 and recombinant VSV/SARS-CoV-2 viruses. We …
SARS-CoV-2 S neutralization escape variants. Mechanistic studies showed that these antibodies

Genetic and structural basis for recognition of SARS-CoV-2 spike protein by a two-antibody cocktail

J Dong, SJ Zost, AJ Greaney, TN Starr, AS Dingens… - BioRxiv, 2021 - biorxiv.org
… to understand the molecular basis for immune recognition of SARS-CoV-2 spike (S) … for
SARS-CoV-2 neutralization, we determined the structures of two human monoclonal antibodies

[HTML][HTML] Structures of human antibodies bound to SARS-CoV-2 spike reveal common epitopes and recurrent features of antibodies

CO Barnes, AP West, KE Huey-Tubman… - Cell, 2020 - cell.com
… Fabs, revealing recognition of both S1 A and RBD epitopes on SARS-CoV-2 … SARS-CoV-2
spike mutations. Overall, our studies structurally define a recurrent anti-SARS-CoV-2 antibody

Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes

WN Voss, YJ Hou, NV Johnson, G Delidakis, JE Kim… - Science, 2021 - science.org
… ” antibodies revealed an NTD epitope that is recurrently mutated among emerging SARS-CoV-2 …
and other non-RBD plasma antibodies are prevalent and have implications for SARS-…

Structural basis for SARS-CoV-2 nucleocapsid protein recognition by single-domain antibodies

Q Ye, S Lu, KD Corbett - Frontiers in immunology, 2021 - frontiersin.org
… -domain antibodies that bind the SARS-CoV-2 Nucleocapsid protein with high affinity. Each
antibody recognizes a specific folded domain of the protein, with two antibodies recognizing

Genetic and structural basis for SARS-CoV-2 variant neutralization by a two-antibody cocktail

J Dong, SJ Zost, AJ Greaney, TN Starr… - Nature …, 2021 - nature.com
antibody-mediated neutralization. Both AZD8895 and AZD1061 have strong neutralizing
activity against SARS-CoV-… -encoded antibody features enable recognition of the SARS-CoV-2 …