… suppress cytokine storm is essential … SARS-CoV-2 and the mechanisms by which cytokine
storm is induced by the virus will be introduced in detail, including the ways in which cytokines …

… cytokine responses caused by these viruses. Our curation indicates that the cytokine response
induced by SARS-CoV-2 … , as SARS-CoV-2 does not always induce specific cytokines like …

… the cytokine storm induced by COVID-19. In addition, we suggest that the identification and
treatment of the cytokine storm … innate responses to SARS-CoV-2 may cause cytokine storms. …

… with severe acute respiratory syndrome coronavirus 2, leading to clinical … to as cytokine
storm in its severest form has been marked by elevation of IL-6, IL-10, TNF-α, and other cytokines …

… The level of IL-6 is found to be significantly elevated in the serum of SARS-COV-2 patients
during cytokine storms. IL-6 inactivates cell-mediated antiviral response by inhibiting the …

… cytokines are likely produced by highly inflammatory macrophages that have been implicated
in cytokine storm … This study demonstrates that cytokine storm is associated with COVID-19 …

… coronavirus 2 (SARS-CoV-2), can trigger a hyperinflammatory state characterized by
elevated cytokine levels known as hypercytokinemia or cytokine storm, … routes of SARS-CoV-2 …

… To explore whether the ORF3a protein of SARS-CoV-2 could trigger cytokine storms, we
treated macrophages with ORF3a lentivirus. The ORF3a protein not only stimulated …

… inflammasome hyperactivation in the pathogenesis of SARS-CoV-2 caused multi organ …
to cytokine storm and cell death by pyroptosis (Fig. 1). First, it is possible that the SARS-CoV-2 …

… SARS-CoV-2 stimulates the secretion of IL-6 and TNF, a pro-inflammatory complex that can
lead to cytokine storm … In SARS-CoV-2 septic shock, severe metabolic cellular abnormalities …