Current status of therapeutic monoclonal antibodies against SARS-CoV-2

S Kumar, A Chandele, A Sharma - PLoS pathogens, 2021 - journals.plos.org
… Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and … and imdevimab) against
SARS-CoV-2 was approved for … against SARS--CoV-2 and its rapidly emerging variants. …

Monoclonal antibodies for COVID-19 therapy and SARS-CoV-2 detection

YC Hwang, RM Lu, SC Su, PY Chiang, SH Ko… - Journal of Biomedical …, 2022 - Springer
… specificity and reliability, monoclonal antibodies (mAbs) … coronavirus 2 (SARS-CoV-2)
and Ab drugs for use as COVID-19 therapeutic agents. The detailed structure of the SARS-CoV-2 …

Monoclonal antibodies against SARS-CoV-2: current scenario and future perspectives

E Quiros-Roldan, S Amadasi, I Zanella, M Degli Antoni… - Pharmaceuticals, 2021 - mdpi.com
… Numerous mAbs have been developed against SARS-CoV 2 and have proven their … describe
the monoclonal antibodies currently authorized for the treatment of the coronavirus disease …

Monoclonal antibody therapies against SARS-CoV-2

D Focosi, S McConnell, A Casadevall… - The Lancet Infectious …, 2022 - thelancet.com
Monoclonal antibodies (mAbs) targeting the spike protein of SARS-CoV-2 have been widely
used in the ongoing COVID-19 pandemic. In this paper, we review the properties of mAbs …

[HTML][HTML] SARS-CoV-2 variant evasion of monoclonal antibodies based on in vitro studies

MG Cox, TP Peacock, WT Harvey, J Hughes… - Nature Reviews …, 2023 - nature.com
Monoclonal antibodies (mAbs) offer a treatment option for … evolution of resistance to
mAbs by SARS-CoV-2, we reviewed … is being reported with new SARS-CoV-2 variants. The …

In vivo monoclonal antibody efficacy against SARS-CoV-2 variant strains

RE Chen, ES Winkler, JB Case, ID Aziati, TL Bricker… - Nature, 2021 - nature.com
… neutralizing antibodies against variant strains of SARS-CoV-2 … activity of a panel of monoclonal
antibodies (mAbs), which … , Regeneron and Lilly, against SARS-CoV-2 variant viruses. …

Neutralisation sensitivity of SARS-CoV-2 omicron subvariants to therapeutic monoclonal antibodies

D Yamasoba, Y Kosugi, I Kimura, S Fujita… - The Lancet Infectious …, 2022 - thelancet.com
… of newly emerging SARS-CoV-2 variants, we suggest the importance of rapid evaluation
of the efficiency of therapeutic monoclonal antibodies against novel SARS-CoV-2 variants. …

[HTML][HTML] The monoclonal antibody combination REGEN-COV protects against SARS-CoV-2 mutational escape in preclinical and human studies

R Copin, A Baum, E Wloga, KE Pascal, S Giordano… - Cell, 2021 - cell.com
… acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Similar to all viruses, SARS-CoV-2
is … neutralizing monoclonal antibodies (mAbs) targeting the SARS-CoV-2 spike protein ( …

[HTML][HTML] Reaction of human monoclonal antibodies to SARS-CoV-2 proteins with tissue antigens: implications for autoimmune diseases

A Vojdani, E Vojdani, D Kharrazian - Frontiers in Immunology, 2021 - frontiersin.org
… immune reactivity of human monoclonal antibody made against SARS-CoV-2 spike protein
and nucleoprotein and rabbit polyclonal antibody made against SARS-CoV-2 envelope and …

Complete map of SARS-CoV-2 RBD mutations that escape the monoclonal antibody LY-CoV555 and its cocktail with LY-CoV016

TN Starr, AJ Greaney, AS Dingens, JD Bloom - Cell Reports Medicine, 2021 - cell.com
antibodies ineffective. Here, we completely map all of the mutations to the SARS-CoV-2 spike
receptor-binding domain (RBD) that escape binding by a leading monoclonal antibody, LY-…