The global epidemic of SARSCoV‐2 variants and their mutational immune escape

D Tian, YH Sun, JM Zhou, Q Ye - Journal of medical virology, 2022 - Wiley Online Library
… These SARS-CoV-2 variants … escape of different SARS-CoV-2 variants. We hope to provide
scientific reference for the monitoring, prevention, and control measures of new SARS-CoV-2 …

Mapping mutations to the SARS-CoV-2 RBD that escape binding by different classes of antibodies

AJ Greaney, TN Starr, CO Barnes, Y Weisblum… - Nature …, 2021 - nature.com
SARS-CoV-2 has already acquired mutations that reduce binding by each antibody class,
we compared the total escape … at the site among sequenced SARS-CoV-2 isolates in GISAID …

Emergence of immune escape at dominant SARS-CoV-2 killer T cell epitope

G Dolton, C Rius, MS Hasan, A Wall, B Szomolay… - Cell, 2022 - cell.com
… Viral escape at prevalent T cell epitopes restricted by high … on a single protein such as
SARS-CoV-2 Spike, providing a strong … for monitoring T cell escape in new SARS-CoV-2 variants. …

Antibody escape and global spread of SARS-CoV-2 lineage A. 27

T Kaleta, L Kern, SL Hong, M Hölzer, G Kochs… - Nature …, 2022 - nature.com
… inferred origin and phenotypic characteristics of SARS-CoV-2 lineage A.… Our data demonstrate
that A.27 can partially escape the … escape variants that threaten global vaccination efforts. …

Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies

Y Cao, J Wang, F Jian, T Xiao, W Song, A Yisimayi… - Nature, 2022 - nature.com
… were performed on the basis of the N×M escape score matrix, in which N is the number of …
sites on the SARS-CoV-2 RBD. Each entry of the matrix A nm refers to the total escape score of …

[HTML][HTML] SARS-CoV-2 variant biology: immune escape, transmission and fitness

AM Carabelli, TP Peacock, LG Thorne… - Nature Reviews …, 2023 - nature.com
… in SARS-CoV-2 immunity, the potential exists for selective pressure to lead to T cell escape,
although the extent to which SARS-CoVSARS-CoV-2 genome, the footprints of T cell escape

The global epidemic of the SARS-CoV-2 delta variant, key spike mutations and immune escape

D Tian, Y Sun, J Zhou, Q Ye - Frontiers in immunology, 2021 - frontiersin.org
… Over the last two decades, SARS -CoV-2 has been the third coronavirus known to cause …
, following SARS-CoV in 2003 and MERS-CoV in 2012 (1–3). Coronavirus disease 2019 (…

[HTML][HTML] Population impact of SARS-CoV-2 variants with enhanced transmissibility and/or partial immune escape

M Bushman, R Kahn, BP Taylor, M Lipsitch… - Cell, 2021 - cell.com
SARS-CoV-2 variants of concern exhibit varying degrees of transmissibility and, in some
cases, escape … the pandemic—especially that of immune escape—has remained a challenge. …

SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape

TN Starr, N Czudnochowski, Z Liu, F Zatta, YJ Park… - Nature, 2021 - nature.com
escape, breadth and potency across a panel of SARS-CoV-2 … a corresponding resistance
to SARS-CoV-2 escape. One of … breadth and are readily escaped by mutations despite high …

[HTML][HTML] Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity

WF Garcia-Beltran, EC Lam, KS Denis, AD Nitido… - Cell, 2021 - cell.com
… 10 globally circulating strains of SARS-CoV-2. Five of the 10 … SARS-CoV and bat-derived
WIV1-CoV, suggesting that a relatively small number of mutations can mediate potent escape