[HTML][HTML] … pathogenesis in patients with COVID-19: a review on viral dissemination, immunotherapeutic options to counter cytokine storm and inflammatory responses

AA Rabaan, SH Al-Ahmed, MA Garout, AM Al-Qaaneh… - Pathogens, 2021 - mdpi.com
… Careful scrutiny on the characteristics of the viral particles, … , including the role of cytokine
storm in generating acute … discussed to control the cytokine storm or hypercytokinemia. …

[HTML][HTML] Severe immunosuppression and not a cytokine storm characterizes COVID-19 infections

KE Remy, M Mazer, DA Striker, AH Ellebedy… - JCI insight, 2020 - ncbi.nlm.nih.gov
… Two divergent hypotheses have been proposed: hyperinflammatory cytokine storm; and
failure of host protective immunity that results in unrestrained viral dissemination and organ …

[HTML][HTML] The potential role of cytokine storm pathway in the clinical course of viral respiratory pandemic

G Murdaca, F Paladin, A Tonacci, S Isola, A Allegra… - Biomedicines, 2021 - mdpi.com
cytokine storm during the infection of these pandemic viruses, … in the election of medical
treatments for these viral diseases. … shows how the cytokine storm may favor viral dissemination. …

Contribution of monocytes and macrophages to the local tissue inflammation and cytokine storm in COVID-19: Lessons from SARS and MERS, and potential …

A Jafarzadeh, P Chauhan, B Saha, S Jafarzadeh… - Life sciences, 2020 - Elsevier
… Both local tissue inflammation and cytokine storm play a key role in the development of …
to support viral dissemination, such as short lifespan and inability to establish viral replication. …

[HTML][HTML] Harnessing the immune system to overcome cytokine storm and reduce viral load in COVID-19: a review of the phases of illness and therapeutic agents

S Khadke, N Ahmed, N Ahmed, R Ratts, S Raju… - Virology journal, 2020 - Springer
… Severe manifestations of COVID-19 are caused by a combination of direct tissue injury
by viral replication and associated cytokine storm resulting in progressive organ damage. …

The cytokine storm in COVID-19: An overview of the involvement of the chemokine/chemokine-receptor system

F Coperchini, L Chiovato, L Croce, F Magri… - Cytokine & growth factor …, 2020 - Elsevier
viruses can interfere with the chemokine/chemokine-receptors system using their own
properties to modify intracellular signaling with the final result to further disseminate the infection. …

[HTML][HTML] Controlling cytokine storm is vital in COVID-19

L Tang, Z Yin, Y Hu, H Mei - Frontiers in immunology, 2020 - frontiersin.org
… Downstream production of interferons promotes intracellular antiviral defenses in neighboring
epithelial cells which may limit viral dissemination, while the release of IL-6 and IL-1β from …

[HTML][HTML] Cytokine storm—definition, causes, and implications

D Jarczak, A Nierhaus - International journal of molecular sciences, 2022 - mdpi.com
… production to fight systemic infection and dysregulated cytokine production. Disseminated
… Different viruses are associated with diverse patterns of cytokine release, but so far, this has …

[HTML][HTML] Quantification of cytokine storms during virus infections

S Yuan, SC Jiang, ZW Zhang, YF Fu, J Hu… - Frontiers in …, 2021 - frontiersin.org
… , hepatitis B virus, hepatitis C virus, and enterovirus 71 were included in this analysis. …
cytokine fold change (FC), viral load, and clearance rate data from these highly pathogenic virus

Cytokine storm induced by SARS-CoV-2

P Song, W Li, J Xie, Y Hou, C You - Clinica chimica acta, 2020 - Elsevier
… Therefore, using strategies to effectively suppress cytokine storm is … by which cytokine storm
is induced by the virus will be … The existence of disseminated intravascular coagulation is …