Constitutive inflammatory cytokine storm: a major threat to human health

KK Gupta, MA Khan, SK Singh - Journal of Interferon & Cytokine …, 2020 - liebertpub.com
Viral infections such as influenza lead to massive stimulation of T cells that result in the
cytokine storm (… This review will focus on the inflammatory cytokine storm and its implications on …

[HTML][HTML] Hypoxemia and cytokine storm in COVID-19: clinical implications

C Machado-Curbelo, A González-Quevedo - MEDICC review, 2022 - SciELO Public Health
… Nonetheless, an important caveat is the possibility of aerosol dissemination, spreading the
virus to health workers and other patients.[ 41 41. Simonds AK, Hanak A, Chatwin M, Morrell …

Cytokine storm associated coagulation complications in COVID-19 patients: Pathogenesis and Management

SR Savla, KS Prabhavalkar, LK Bhatt - Expert review of anti …, 2021 - Taylor & Francis
… This leads to diffuse/disseminated intravascular coagulation (DIC), which is a characteristic
… the use of anti-viral and supportive therapeutic agents. Cytokine storm has been commonly …

Role of SARS-CoV-2-induced cytokine storm in multi-organ failure: Molecular pathways and potential therapeutic options

Y Nazerian, M Ghasemi, Y Yassaghi, A Nazerian… - International …, 2022 - Elsevier
… COVID-19-related cytokine storm and its association with multi-… therapeutic targets to control
cytokine storm wishing to answer … cytokines that have a prominent role in acute viral disease …

[PDF][PDF] Is COVID-19 a cytokine storm driven viral sepsis?

R Gupta - Polymorphism, 2020 - researchgate.net
… with cytokine storm and hypercoagulation/viral load on higher side. On the contrary, only
anti-virals should be good for asymptomatic RT-PCR positive patients. However, more basic …

Pathogenesis and treatment of cytokine storm in COVID-19

M Soy, G Keser, MP Atagündüz - Turkish Journal of Biology, 2021 - journals.tubitak.gov.tr
… A hyperinflammatory state resulting in a cytokine storm and adult respiratory distress …
cytokine storm (COVID-CS). Insufficient viral clearance and persistence of a strong cytokine

Cytokine storm in the pathophysiology of COVID-19: Possible functional disturbances of miRNAs

M Aslani, SS Mortazavi-Jahromi, A Mirshafiey - International …, 2021 - Elsevier
… This can be arisen from virus-induced interfering factors (Table 1) subsequently leading
to increased viral replication, continuous inflammation, and cytokine storm. Identification, …

Interplay between interleukin-6 signaling and the vascular endothelium in cytokine storms

S Kang, T Kishimoto - Experimental & molecular medicine, 2021 - nature.com
… Thus, increased cytokine production controls some disseminated infections; however, …
HHV-8 encodes a homolog of human IL-6, referred to as viral IL-6 (vIL-6), which is produced by …

[PDF][PDF] Treatment of the Cytokine Storm in COVID-19

B Halacli, A Topeli - J Crit Intensive Care, 2020 - researchgate.net
… Although there is still insufficient evidence, several antiviral … of inflammatory cytokines
necessary for virus clearance (14). … necrotising vasculitis, disseminated intravascular coagulation, …

… cytokines in COVID-19 patients: A review on molecular mechanisms, immune functions, immunopathology and immunomodulatory drugs to counter cytokine storm

AA Rabaan, SH Al-Ahmed, J Muhammad, A Khan… - Vaccines, 2021 - mdpi.com
… The vicious tentacles of the disease have been disseminated worldwide with unknown …
more cytokines, leading to the cytokine storm. The increasing viral load activates more cytokines, …