On the alert for cytokine storm: immunopathology in COVID‐19

LA Henderson, SW Canna, GS Schulert… - Arthritis & …, 2020 - Wiley Online Library
… from other forms of viral-induced cytokine storm, in that ferritin … the virus for the lung. However,
critically ill patients with COVID-19 often demonstrate features suggestive of cytokine storm

Cytokine responses to adenovirus and adenovirus vectors

S Atasheva, DM Shayakhmetov - Viruses, 2022 - mdpi.com
Cytokine-mediated toxicity and cytokine storm are known clinical phenomena observed
following naturally disseminated adenovirus infection in immunocompromised hosts as well as …

Sensing of SARS-CoV-2 by pDCs and their subsequent production of IFN-I contribute to macrophage-induced cytokine storm during COVID-19

P Laurent, C Yang, AF Rendeiro… - Science …, 2022 - science.org
… The role of type I interferon (IFN-I) in protection from viral dissemination of SARS-CoV-2 is
well documented, because patients with defects in IFN-I or IFN-III responses (12, 20, 21) or …

STAT2 signaling restricts viral dissemination but drives severe pneumonia in SARS-CoV-2 infected hamsters

R Boudewijns, HJ Thibaut, SJF Kaptein, R Li… - Nature …, 2020 - nature.com
… In humans, SARS-CoV-2 infection begins frequently with a flu-like illness, followed in a
second phase by an intense inflammatory response characterized by a cytokine storm and acute …

Unraveling the mystery of Covid‐19 cytokine storm: From skin to organ systems

S Garg, M Garg, N Prabhakar, P Malhotra… - Dermatologic …, 2020 - Wiley Online Library
… on in more severe cases, later presenting as disseminated intravascular coagulation (DIC).
Now, besides alveolar capillaries, whether the virus is able to gain entry into the small blood …

[PDF][PDF] Cytokines storm of COVID-19 and multi systemic organ failure: A review

ZNM Albarzanji, TA Mahmood, ER Sarhat… - Sys Rev Pharm, 2020 - academia.edu
… protein called Disseminated intravascular coagulation (DIC). … responder mechanisms
induced by the virus (T lymphocyte or … Third, the cytokines or mediators induced by the virus may …

Basic predictive risk factors for cytokine storms in COVID-19 patients

SG Shcherbak, AY Anisenkova, SV Mosenko… - Frontiers in …, 2021 - frontiersin.org
… ), features of viral pneumonia seen on unenhanced lung … disseminated intravascular
coagulation, symptom-related treatment, and oxygen therapy. To prevent or treat the cytokine storm

Signaling pathways in the regulation of cytokine release syndrome in human diseases and intervention therapy

X Li, M Shao, X Zeng, P Qian, H Huang - Signal Transduction and …, 2021 - nature.com
… In 1993, Ferrara et al. coined the term ‘cytokine storm’ to describe the … Later, cytokine storm
was also known as cytokine release … epithelial cells which may limit viral dissemination. …

Early control of viral load by favipiravir promotes survival to Ebola virus challenge and prevents cytokine storm in non-human primates

S Reynard, E Gloaguen, N Baillet… - PLoS Neglected …, 2021 - journals.plos.org
… show that the cytokine/chemokine storm correlates with the excessive viral load. However, …
the environment responsible for the disseminated intravascular coagulation observed in EVD […

The looming storm: blood and cytokines in COVID-19

S Kaur, R Bansal, S Kollimuttathuillam, AM Gowda… - Blood reviews, 2021 - Elsevier
… abnormalities including cytokine storm, hypercoagulable state … drugs targeting
cytokine storm in patients with SARS-CoV-2. … target of viruses through ACE2 receptor, b)Cytokine-induced …