… Genomic and subgenomic RNA synthesis takes place in the synthesis of viralproteins. Then, with the help of ribosomes, viral RNAs are transmitted and viralproteins are synthesized. 8. …
R Gorkhali, P Koirala, S Rijal… - … and biology insights, 2021 - journals.sagepub.com
… The sequencing revealed that the novel virus had most proteins homologous to SARS-CoV, … (I) Finally, replicated RNA and other translated viralproteins assembled into a new virus. …
C Vazquez, SE Swanson, SG Negatu, M Dittmar… - PloS one, 2021 - journals.plos.org
… Here, we show that SARS-CoV-2 can block IRF3 and NF-κB activation early during virus infection. We also identify that the SARS-CoV-2 viralproteins NSP1 and NSP13 can block …
J Zhang, R Cruz-Cosme, MW Zhuang, D Liu… - Signal transduction and …, 2020 - nature.com
… We identified ORF3a to be the viralprotein that is associated with the formation of … SARS-CoV-2 and applied a systemic IFA to characterize the subcellular distribution of the viralproteins…
A Tidu, A Janvier, L Schaeffer, P Sosnowski, L Kuhn… - Rna, 2021 - rnajournal.cshlp.org
… Here, we confirm that viral translation is maintained in the presence of NSP1 and we show … 5′UTR of SARS-CoV-2. Only the apical part of SL1 is required for viral translation. We further …
H Yang, Z Rao - Nature Reviews Microbiology, 2021 - nature.com
… In this Review, we delineate the structural features of SARS-CoV-2 from the whole viral particle to the individual viralproteins and discuss their functions as well as their potential as …
… associated with membrane such as S, M, and E are synthesized by endoplasmic reticulum-bound ribosomes, whereas other viralproteins, including N protein, are translated by free …
J Zhang, T Xiao, Y Cai, B Chen - Current opinion in virology, 2021 - Elsevier
… of viralproteins and relevant host factors. The trimeric spike (S) … viral entry process. Here we summarize our current knowledge on the structure of the SARS-CoV-2 S protein …
S Wu, C Tian, P Liu, D Guo, W Zheng… - Journal of medical …, 2021 - Wiley Online Library
… Overall, our findings suggest that SARS-CoV-2 mutations could change viralprotein structure, binding affinity, and hot spots of the interface, thereby might have impacts on …