… We identify previously unknown cleavage sites in multiple viral proteins, including major
antigens S and N: the main targets for vaccine and antibody testing efforts. We discover …

… (N) protein [7], which is the most abundant viral protein in … N protein phase separates with
genomic RNA of SARS-CoV-2, which may play an important role in the packaging of new viral …

… of SARS-CoV-2 (and indeed studies of most other viruses) have focused on viral proteins. For
… the receptor-binding domain of the spike protein of SARS-CoV-2 bound to the cell receptor …

… VSV/SARS-CoV-2 reporter virus, we show that functional SARS-CoV-2 S protein variants with
… that target specific segments of viral proteins can neutralize virus particles and trigger the …

… We therefore hypothesized that TLR2 recognizes viral proteins from β-coronaviruses as well.
To investigate whether viral proteins independent of functioning virions could activate TLR2…

… Finally, we examined homology between SARS-CoV and SARS-CoV-2 in 15 viral proteins
shown to be interferon antagonist. The absence of open reading frame (ORF) 3b 16 and …

… genome, immune evasion as well as in processing of viral proteins and … for virus replication
- the protein encoded by the SARS-CoV-2 ORF8 gene and those encoded by the SARS-CoV …

… viruses by delivering viruses and viral proteins to lysosomes for degradation. Therefore,
viruses can interfere with protein … concentration and function of viral proteins. H1N1 blocks …

… We also describe the mechanisms by which SARS-CoV-2 viral proteins promote host
shutoff. A detailed understanding of the host-pathogen interactions that unbalance the IFN …

… by the closely related SARS‐CoV virus, 4 and the SARS‐CoV‐2 N protein is considered a
… stress granules, enhance viral replication or translation of viral proteins, and package the …