A physiologically based pharmacokinetic modeling approach to predict disease–drug interactions: suppression of CYP3A by IL‐6

KK Machavaram, LM Almond… - Clinical …, 2013 - Wiley Online Library
Elevated cytokine levels are known to downregulate expression and suppress activity of
cytochrome P450 enzymes (CYPs). Cytokine‐modulating therapeutic proteins (TPs) used in …
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A physiologically based pharmacokinetic modeling approach to predict disease-drug interactions: suppression of CYP3A by IL-6

KK Machavaram, LM Almond… - Clinical …, 2013 - pubmed.ncbi.nlm.nih.gov
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[引用][C] A Physiologically Based Pharmacokinetic Modeling Approach to Predict Disease―Drug Interactions: Suppression of CYP3A by IL-6

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