Design, synthesis, and evaluation of liver-specific gemcitabine prodrugs for potential treatment of hepatitis C virus infection and hepatocellular carcinoma

AA Stephenson, S Cao, DJ Taggart… - European Journal of …, 2021 - Elsevier
Many successful anti-viral and anti-cancer drugs are nucleoside analogs, which disrupt RNA
and/or DNA synthesis. Here, we present liver-specific prodrugs of the chemotherapy drug …

Design, synthesis, and evaluation of liver-specific gemcitabine prodrugs for potential treatment of hepatitis C virus infection and hepatocellular carcinoma.

AA Stephenson, S Cao, DJ Taggart… - European Journal of …, 2021 - europepmc.org
Many successful anti-viral and anti-cancer drugs are nucleoside analogs, which disrupt RNA
and/or DNA synthesis. Here, we present liver-specific prodrugs of the chemotherapy drug …

Design, synthesis, and evaluation of liver-specific gemcitabine prodrugs for potential treatment of hepatitis C virus infection and hepatocellular carcinoma

AA Stephenson, S Cao, DJ Taggart… - European journal …, 2021 - pubmed.ncbi.nlm.nih.gov
Many successful anti-viral and anti-cancer drugs are nucleoside analogs, which disrupt RNA
and/or DNA synthesis. Here, we present liver-specific prodrugs of the chemotherapy drug …

Design, synthesis, and evaluation of liver-specific gemcitabine prodrugs for potential treatment of hepatitis C virus infection and hepatocellular carcinoma.

AA Stephenson, S Cao, DJ Taggart, VP Vyavahare… - 2021 - cabidigitallibrary.org
Many successful anti-viral and anti-cancer drugs are nucleoside analogs, which disrupt RNA
and/or DNA synthesis. Here, we present liver-specific prodrugs of the chemotherapy drug …