Transport vs. metabolism: what determines the pharmacokinetics and pharmacodynamics of drugs? Insights from the extended clearance model

Clinical Pharmacology & Therapeutics, 2016 - Wiley Online Library
The well‐stirred hepatic clearance model (WSHM) has been expanded to include drug
transporters (ie, extended clearance model [ECM]). However, the consequences of this …

[HTML][HTML] Transport vs. metabolism: what determines the pharmacokinetics (PK) and pharmacodynamics (PD) of drugs? Insights from the extended clearance model

G Patilea-Vrana, JD Unadkat - Clinical pharmacology and …, 2016 - ncbi.nlm.nih.gov
The well-stirred hepatic clearance model (WSHM) has been expanded to include drug
transporters (ie extended clearance model [ECM]). But, the consequences of this expansion …

Transport vs. Metabolism: What Determines the Pharmacokinetics and Pharmacodynamics of Drugs? Insights From the Extended Clearance Model

G Patilea-Vrana, JD Unadkat - Clinical pharmacology …, 2016 - pubmed.ncbi.nlm.nih.gov
The well-stirred hepatic clearance model (WSHM) has been expanded to include drug
transporters (ie, extended clearance model [ECM]). However, the consequences of this …

Transport vs. Metabolism: What Determines the Pharmacokinetics and Pharmacodynamics of Drugs? Insights From the Extended Clearance Model.

G Patilea‐Vrana, JD Unadkat - Clinical Pharmacology & …, 2016 - search.ebscohost.com
The well-stirred hepatic clearance model (WSHM) has been expanded to include drug
transporters (ie, extended clearance model [ECM]). However, the consequences of this …

[PDF][PDF] Transport vs. metabolism: what determines the pharmacokinetics (PK) and pharmacodynamics (PD) of drugs? Insights from the extended clearance model

G Patilea-Vrana, JD Unadkat - Clin Pharmacol Ther, 2016 - researchgate.net
The well-stirred hepatic clearance model (WSHM) has been expanded to include drug
transporters (ie extended clearance model [ECM]). But, the consequences of this expansion …

Transport vs. Metabolism: What Determines the Pharmacokinetics and Pharmacodynamics of Drugs? Insights From the Extended Clearance Model.

G Patilea-Vrana, JD Unadkat - Clinical Pharmacology and …, 2016 - europepmc.org
The well-stirred hepatic clearance model (WSHM) has been expanded to include drug
transporters (ie, extended clearance model [ECM]). However, the consequences of this …

Transport vs. Metabolism: What Determines the Pharmacokinetics and Pharmacodynamics of Drugs? Insights From the Extended Clearance Model.

G Patilea-Vrana, JD Unadkat - Clinical Pharmacology and …, 2016 - europepmc.org
The well-stirred hepatic clearance model (WSHM) has been expanded to include drug
transporters (ie extended clearance model [ECM]). But, the consequences of this expansion …