Probing the effects of residues located outside the agonist binding site on drug-receptor selectivity in the nicotinic receptor

NL Puskar, HA Lester, DA Dougherty - ACS chemical biology, 2012 - ACS Publications
The nicotinic acetylcholine receptors (nAChRs) are a family of closely related but
pharmacologically distinct neurotransmitter-gated ion channels. They are therapeutic targets …

[HTML][HTML] Probing the Effects of Residues Located Outside the Agonist Binding Site on Drug-Receptor Selectivity in the Nicotinic Receptor

NL Puskar, HA Lester, DA Dougherty - ACS Chemical Biology, 2012 - ncbi.nlm.nih.gov
The nicotinic acetylcholine receptors (nAChRs) are a family of closely related but
pharmacologically distinct neurotransmitter-gated ion channels. They are therapeutic targets …

[PDF][PDF] Probing the Effects of Residues Located Outside the Agonist Binding Site on Drug-Receptor Selectivity in the Nicotinic Receptor

NL Puskar, HA Lester, DA Dougherty - academia.edu
The nicotinic acetylcholine receptors (nAChRs) are a family of closely related but
pharmacologically distinct neurotransmitter-gated ion channels. They are therapeutic targets …

[PDF][PDF] Probing the Effects of Residues Located Outside the Agonist Binding Site on Drug-Receptor Selectivity in the Nicotinic Receptor

NL Puskar, HA Lester… - ACS Chemical …, 2012 - authors.library.caltech.edu
The nicotinic acetylcholine receptors (nAChRs) are a family of closely related but
pharmacologically distinct neurotransmitter-gated ion channels. They are therapeutic targets …

[PDF][PDF] Probing the Effects of Residues Located Outside the Agonist Binding Site on Drug-Receptor Selectivity in the Nicotinic Receptor

NL Puskar, HA Lester, DA Dougherty - core.ac.uk
Table S1: EC50 values (µM) and Hill coefficients for mutant (α1) 2β1γδ nAChRs Table S2:
EC50 values (µM) and Hill coefficients for mutant (α7) 5 nAChRs Table S3: EC50 values …

Probing the effects of residues located outside the agonist binding site on drug-receptor selectivity in the nicotinic receptor.

NL Puskar, HA Lester, DA Dougherty - ACS Chemical Biology, 2012 - europepmc.org
The nicotinic acetylcholine receptors (nAChRs) are a family of closely related but
pharmacologically distinct neurotransmitter-gated ion channels. They are therapeutic targets …

Probing the effects of residues located outside the agonist binding site on drug-receptor selectivity in the nicotinic receptor

NL Puskar, HA Lester… - ACS chemical …, 2012 - pubmed.ncbi.nlm.nih.gov
The nicotinic acetylcholine receptors (nAChRs) are a family of closely related but
pharmacologically distinct neurotransmitter-gated ion channels. They are therapeutic targets …

[PDF][PDF] Probing the Effects of Residues Located Outside the Agonist Binding Site on Drug-Receptor Selectivity in the Nicotinic Receptor

NL Puskar, HA Lester, DA Dougherty - authors.library.caltech.edu
The nicotinic acetylcholine receptors (nAChRs) are a family of closely related but
pharmacologically distinct neurotransmitter-gated ion channels. They are therapeutic targets …