Investigating the ibrutinib resistance mechanism of L528W mutation on Brutonʼs tyrosine kinase via molecular dynamics simulations

B Xu, L Liang, Y Jiang, Z Zhao - Journal of Molecular Graphics and …, 2024 - Elsevier
Drug resistance to Bruton's Tyrosine Kinase (BTK) inhibitors presents a challenge in treating
B-cell malignancies, and the mechanism behind drug resistance remains unclear. In this …
被引用次数：1 相关文章

Investigating the ibrutinib resistance mechanism of L528W mutation on Bruton's tyrosine kinase via molecular dynamics simulations.

B Xu, L Liang, Y Jiang, Z Zhao - Journal of Molecular Graphics & …, 2023 - europepmc.org
Drug resistance to Bruton's Tyrosine Kinase (BTK) inhibitors presents a challenge in treating
B-cell malignancies, and the mechanism behind drug resistance remains unclear. In this …

Investigating the ibrutinib resistance mechanism of L528W mutation on Bruton's tyrosine kinase via molecular dynamics simulations

B Xu, L Liang, Y Jiang, Z Zhao - Journal of molecular graphics & … - pubmed.ncbi.nlm.nih.gov
Drug resistance to Bruton's Tyrosine Kinase (BTK) inhibitors presents a challenge in treating
B-cell malignancies, and the mechanism behind drug resistance remains unclear. In this …