Antigen cross-presentation in young tumor-bearing hosts promotes CD8+ T cell terminal differentiation

A Moustaki, JC Crawford, S Alli, Y Fan, S Boi… - Science …, 2022 - science.org
The immune system undergoes a progressive functional remodeling with age.
Understanding how age bias shapes antitumor immunity is essential in designing effective …

Antigen cross-presentation in young tumor-bearing hosts promotes CD8+ T cell terminal differentiation.

A Moustaki, JC Crawford, S Alli, Y Fan… - Science …, 2022 - search.ebscohost.com
To focus on the interaction of CD8 SP+ sp T cells with the tumor-infiltrated APCs, we
eliminated the cross-talk between CD8 SP+ sp T cells and tumor cells by knocking out the …

Antigen cross-presentation in young tumor-bearing hosts promotes CD8+ T cell terminal differentiation.

A Moustaki, JC Crawford, S Alli, Y Fan, S Boi… - Science …, 2022 - europepmc.org
The immune system undergoes a progressive functional remodeling with age.
Understanding how the age bias shapes anti-tumor immunity is essential in designing …

Antigen cross-presentation in young tumor-bearing hosts promotes CD8+ T cell terminal differentiation

A Moustaki, JC Crawford, S Alli, Y Fan… - Science …, 2022 - pubmed.ncbi.nlm.nih.gov
The immune system undergoes a progressive functional remodeling with age.
Understanding how age bias shapes antitumor immunity is essential in designing effective …

[HTML][HTML] Antigen cross-presentation in young tumor-bearing hosts promotes CD8+ T cell terminal differentiation

A Moustaki, JC Crawford, S Alli, Y Fan, S Boi… - Science …, 2022 - ncbi.nlm.nih.gov
The immune system undergoes a progressive functional remodeling with age.
Understanding how the age bias shapes anti-tumor immunity is essential in designing …