Characterization of genomic regulation profiles in human mitral valve whole tissue to annotate genetic risk loci for mitral valve prolapse
Rationale Mitral valve prolapse (MVP) is a common valve disease that leads to mitral
insufficiency, heart failure and sudden death. The identification of risk loci provided insight …
insufficiency, heart failure and sudden death. The identification of risk loci provided insight …
Characterization of genomic regulation profiles in human mitral valve whole tissue to annotate genetic risk loci for mitral valve prolapse
S Kyryachenko, A Georges, M Yu, T Barrandou… - 2020 - europepmc.org
Objective To establish the chromatin accessibility profiles and gene regulation specificities
of human mitral valve and identify functional variants and target genes at MVP loci. Methods …
of human mitral valve and identify functional variants and target genes at MVP loci. Methods …
[PDF][PDF] Characterization of genomic regulation profiles in human mitral valve whole tissue to annotate genetic risk loci for mitral valve prolapse 2
S Kyryachenko, A Georges, M Yu, T Barrandou… - scholar.archive.org
Objective: To establish the chromatin accessibility profiles and gene regulation specificities
of 32 human mitral valve and identify functional variants and target genes at MVP loci. 33 …
of 32 human mitral valve and identify functional variants and target genes at MVP loci. 33 …