MODULATING TFEB ACTIVITY IN THE BIRT-HOGG-DUBE'SYNDROME BY TARGETING THE VACUOLAR ATPASE
2023 - air.unimi.it
The transcription factor EB (TFEB) is a master regulator of lysosome biogenesis and
autophagy, and its activity is primarily controlled by the kinase complex mTORC1. In the Birt …
autophagy, and its activity is primarily controlled by the kinase complex mTORC1. In the Birt …
[PDF][PDF] Modulating TFEB activity in the Birt-Hogg-Dubé syndrome by targeting the vacuolar ATPase
C Vilardo - 2023 - air.unimi.it
The microphthalmia transcription factors (MiT/TFE) belong to the basic helix-loophelix
leucine zipper (bHLH-LZ) family of proteins. In vertebrates, the MiT/TFE family is composed …
leucine zipper (bHLH-LZ) family of proteins. In vertebrates, the MiT/TFE family is composed …