Overcoming the shortcomings of the extended-clearance concept: a framework for developing a physiologically-based pharmacokinetic (PBPK) model to select drug …

X Liang, Y Lai - Expert Opinion on Drug Metabolism & Toxicology, 2021 - Taylor & Francis
Introduction: Human pharmacokinetic (PK) prediction can be a significant challenge to drug
candidates undergoing transporter-mediated clearance, when only animal data and in vitro …
被引用次数：9 相关文章

Overcoming the shortcomings of the extended-clearance concept: a framework for developing a physiologically-based pharmacokinetic (PBPK) model to select drug …

X Liang, Y Lai - Expert opinion on drug metabolism & …, 2021 - pubmed.ncbi.nlm.nih.gov
Introduction: Human pharmacokinetic (PK) prediction can be a significant challenge to drug
candidates undergoing transporter-mediated clearance, when only animal data and in vitro …

Overcoming the shortcomings of the extended-clearance concept: a framework for developing a physiologically-based pharmacokinetic (PBPK) model to select drug …

X Liang, Y Lai - Expert Opinion on Drug Metabolism & Toxicology, 2021 - europepmc.org
Introduction: Human pharmacokinetic (PK) prediction can be a significant challenge to drug
candidates undergoing transporter-mediated clearance, when only animal data and in vitro …