[HTML][HTML] SomaticCombiner: improving the performance of somatic variant calling based on evaluation tests and a consensus approach

M Wang, W Luo, K Jones, X Bian, R Williams… - Scientific reports, 2020 - nature.com
It is challenging to identify somatic variants from high-throughput sequence reads due to
tumor heterogeneity, sub-clonality, and sequencing artifacts. In this study, we evaluated the …

[PDF][PDF] SomaticCombiner: improving the performance of somatic variant calling based on evaluation tests and a consensus approach

M Wang1Ε, W Luo, K Jones, X Bian, R Williams… - Scientific Reports, 2020 - d-nb.info
Results Datasets for evaluation. In order to evaluate the performance of individual callers
and ensemble approaches, we started benchmark tests with four synthetic DREAM WGS …

SomaticCombiner: improving the performance of somatic variant calling based on evaluation tests and a consensus approach

M Wang, W Luo, K Jones, X Bian… - Scientific …, 2020 - ui.adsabs.harvard.edu
It is challenging to identify somatic variants from high-throughput sequence reads due to
tumor heterogeneity, sub-clonality, and sequencing artifacts. In this study, we evaluated the …

SomaticCombiner: improving the performance of somatic variant calling based on evaluation tests and a consensus approach.

M Wang, W Luo, K Jones, X Bian, R Williams… - Scientific …, 2020 - europepmc.org
It is challenging to identify somatic variants from high-throughput sequence reads due to
tumor heterogeneity, sub-clonality, and sequencing artifacts. In this study, we evaluated the …

SomaticCombiner: improving the performance of somatic variant calling based on evaluation tests and a consensus approach

M Wang, W Luo, K Jones, X Bian… - Scientific …, 2020 - pubmed.ncbi.nlm.nih.gov
It is challenging to identify somatic variants from high-throughput sequence reads due to
tumor heterogeneity, sub-clonality, and sequencing artifacts. In this study, we evaluated the …

SomaticCombiner: improving the performance of somatic variant calling based on evaluation tests and a consensus approach.

M Wang, W Luo, K Jones, X Bian… - Scientific …, 2020 - search.ebscohost.com
It is challenging to identify somatic variants from high-throughput sequence reads due to
tumor heterogeneity, sub-clonality, and sequencing artifacts. In this study, we evaluated the …

[HTML][HTML] SomaticCombiner: improving the performance of somatic variant calling based on evaluation tests and a consensus approach

M Wang, W Luo, K Jones, X Bian, R Williams… - Scientific …, 2020 - ncbi.nlm.nih.gov
It is challenging to identify somatic variants from high-throughput sequence reads due to
tumor heterogeneity, sub-clonality, and sequencing artifacts. In this study, we evaluated the …

SomaticCombiner: improving the performance of somatic variant calling based on evaluation tests and a consensus approach.

M Wang, W Luo, K Jones, X Bian, R Williams… - Scientific …, 2020 - europepmc.org
It is challenging to identify somatic variants from high-throughput sequence reads due to
tumor heterogeneity, sub-clonality, and sequencing artifacts. In this study, we evaluated the …