Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing

N Kessler, SF Viehmann, C Krollmann, K Mai… - Journal of Experimental …, 2022 - rupress.org
Autoimmune vasculitis is a group of life-threatening diseases, whose underlying pathogenic
mechanisms are incompletely understood, hampering development of targeted therapies …

Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing

N Kessler, SF Viehmann… - Journal of …, 2022 - epub.ub.uni-muenchen.de
Kessler et al. identify aberrant DNA recognition by cGAS/STING and IFN-I production by
inflammatory macrophages as a driver of severe ANCA-associated vasculitis …

[HTML][HTML] Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing

N Kessler, SF Viehmann, C Krollmann… - The Journal of …, 2022 - ncbi.nlm.nih.gov
Autoimmune vasculitis is a group of life-threatening diseases, whose underlying pathogenic
mechanisms are incompletely understood, hampering development of targeted therapies …

Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing

N Kessler, SF Viehmann, C Krollmann, K Mai… - bioRxiv, 2022 - biorxiv.org
Autoimmune vasculitis is a group of life-threatening diseases, whose underlying pathogenic
mechanisms are incompletely understood, hampering development of targeted therapies …

Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing

N Kessler, SF Viehmann, C Krollmann… - Journal Of …, 2022 - infoscience.epfl.ch
Kessler et al. identify aberrant DNA recognition by cGAS/STING and IFN-I production by
inflammatory macrophages as a driver of severe ANCA-associated vasculitis …

Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing

N Kessler, SF Viehmann, C Krollmann, K Mai… - The Journal of …, 2022 - pure.mpg.de
Autoimmune vasculitis is a group of life-threatening diseases, whose underlying pathogenic
mechanisms are incompletely understood, hampering development of targeted therapies …

Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing.

N Kessler, SF Viehmann, C Krollmann, K Mai… - 2022 - mediatum.ub.tum.de
Autoimmune vasculitis is a group of life-threatening diseases, whose underlying pathogenic
mechanisms are incompletely understood, hampering development of targeted therapies …

Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing

N Kessler, SF Viehmann, C Krollmann… - The Journal of …, 2022 - research.rug.nl
Autoimmune vasculitis is a group of life-threatening diseases, whose underlying pathogenic
mechanisms are incompletely understood, hampering development of targeted therapies …

Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing

N Kessler, SF Viehmann… - The Journal of …, 2022 - pubmed.ncbi.nlm.nih.gov
Autoimmune vasculitis is a group of life-threatening diseases, whose underlying pathogenic
mechanisms are incompletely understood, hampering development of targeted therapies …

[PDF][PDF] Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing

N Kessler, SF Viehmann, C Krollmann, K Mai… - J. Exp. Med, 2022 - core.ac.uk
Autoimmune vasculitis is a group of life-threatening diseases, whose underlying pathogenic
mechanisms are incompletely understood, hampering development of targeted therapies …