Predicting changes in the pharmacokinetics of CYP3A‐metabolized drugs in hepatic impairment and insights into factors driving these changes

MK Ladumor, F Storelli, X Liang, Y Lai… - CPT …, 2023 - Wiley Online Library
Physiologically based pharmacokinetic models, populated with drug‐metabolizing enzyme
and transporter (DMET) abundance, can be used to predict the impact of hepatic impairment …

Predicting changes in the pharmacokinetics of CYP3A-metabolized drugs in hepatic impairment and insights into factors driving these changes.

MK Ladumor, F Storelli, X Liang, Y Lai… - CPT …, 2022 - europepmc.org
Physiologically based pharmacokinetic models, populated with drug‐metabolizing enzyme
and transporter (DMET) abundance, can be used to predict the impact of hepatic impairment …

[HTML][HTML] Predicting changes in the pharmacokinetics of CYP3A‐metabolized drugs in hepatic impairment and insights into factors driving these changes

MK Ladumor, F Storelli, X Liang, Y Lai… - CPT …, 2023 - ncbi.nlm.nih.gov
Physiologically based pharmacokinetic models, populated with drug‐metabolizing enzyme
and transporter (DMET) abundance, can be used to predict the impact of hepatic impairment …

Predicting changes in the pharmacokinetics of CYP3A-metabolized drugs in hepatic impairment and insights into factors driving these changes

MK Ladumor, F Storelli, X Liang, Y Lai… - CPT …, 2023 - search.proquest.com
Physiologically based pharmacokinetic models, populated with drug-metabolizing enzyme
and transporter (DMET) abundance, can be used to predict the impact of hepatic impairment …

Predicting changes in the pharmacokinetics of CYP3A-metabolized drugs in hepatic impairment and insights into factors driving these changes

MK Ladumor, F Storelli, X Liang… - CPT …, 2023 - pubmed.ncbi.nlm.nih.gov
Physiologically based pharmacokinetic models, populated with drug-metabolizing enzyme
and transporter (DMET) abundance, can be used to predict the impact of hepatic impairment …

Predicting changes in the pharmacokinetics of CYP3A-metabolized drugs in hepatic impairment and insights into factors driving these changes.

MK Ladumor, F Storelli, X Liang, Y Lai… - CPT …, 2022 - europepmc.org
Physiologically based pharmacokinetic models, populated with drug-metabolizing enzyme
and transporter (DMET) abundance, can be used to predict the impact of hepatic impairment …