Quantitative prediction of the impact of drug interactions and genetic polymorphisms on cytochrome P450 2C9 substrate exposure

AC Castellan, M Tod, F Gueyffier, M Audars… - Clinical …, 2013 - Springer
Abstract Background and Objective Cytochrome P450 (CYP) 2C9 is the most common
CYP2C enzyme and makes up approximately onethird of total CYP protein content in the …
被引用次数：34 相关文章

Quantitative prediction of the impact of drug interactions and genetic polymorphisms on cytochrome P450 2C9 substrate exposure

AC Castellan, M Tod, F Gueyffier, M Audars… - Clinical …, 2013 - hero.epa.gov
BACKGROUND AND OBJECTIVE: Cytochrome P450 (CYP) 2C9 is the most common
CYP2C enzyme and makes up approximately onethird of total CYP protein content in the …

[引用][C] Quantitative Prediction of the Impact of Drug Interactions and Genetic Polymorphisms on Cytochrome P450 2C9 Substrate Exposure

AC Castellan, M Tod, F Gueyffier, M Audars… - Clinical …, 2013 - cir.nii.ac.jp
Quantitative Prediction of the Impact of Drug Interactions and Genetic Polymorphisms on
Cytochrome P450 2C9 Substrate Exposure | CiNii Research CiNii 国立情報学研究所 学術情報 …

Quantitative Prediction of the Impact of Drug Interactions and Genetic Polymorphisms on Cytochrome P450 2C9 Substrate Exposure

AC Castellan, M Tod, F Gueyffier, M Audars… - Clinical …, 2013 - infona.pl
Background and Objective Cytochrome P450 (CYP) 2C9 is the most common CYP2C
enzyme and makes up approximately onethird of total CYP protein content in the liver. It …

Quantitative Prediction of the Impact of Drug Interactions and Genetic Polymorphisms on Cytochrome P450 2C9 Substrate Exposure

AC Castellan, M Tod, F Gueyffier… - Clinical …, 2013 - search.proquest.com
Abstract Cytochrome P450 (CYP) 2C9 is the most common CYP2C enzyme and makes up
approximately onethird of total CYP protein content in the liver. It metabolises more than 100 …

[引用][C] Quantitative Prediction of the Impact of Drug Interactions and Genetic Polymorphisms on Cytochrome P450 2C9 Substrate Exposure

AC Castellan, M Tod, F Gueyffier… - Clinical …, 2013 - univ-lyon1.hal.science
Quantitative Prediction of the Impact of Drug Interactions and Genetic Polymorphisms on
Cytochrome P450 2C9 Substrate Exposure - Université Claude Bernard Lyon 1 Accéder …

Quantitative prediction of the impact of drug interactions and genetic polymorphisms on cytochrome P450 2C9 substrate exposure

AC Castellan, M Tod, F Gueyffier… - Clinical …, 2013 - pubmed.ncbi.nlm.nih.gov
Background and objective Cytochrome P450 (CYP) 2C9 is the most common CYP2C
enzyme and makes up approximately onethird of total CYP protein content in the liver. It …

[引用][C] Quantitative Prediction of the Impact of Drug Interactions and Genetic Polymorphisms on Cytochrome P450 2C9 Substrate Exposure

AC Castellan, M Tod, F Gueyffier, M Audars… - Clinical …, 2013 - hal.science
Quantitative Prediction of the Impact of Drug Interactions and Genetic Polymorphisms on
Cytochrome P450 2C9 Substrate Exposure - Archive ouverte HAL Accéder directement au …

Quantitative Prediction of the Impact of Drug Interactions and Genetic Polymorphisms on Cytochrome P450 2C9 Substrate Exposure.

AC Castellan, M Tod, F Gueyffier… - Clinical …, 2013 - search.ebscohost.com
Abstract Background and Objective: Cytochrome P450 (CYP) 2C9 is the most common
CYP2C enzyme and makes up approximately onethird of total CYP protein content in the …

Quantitative prediction of the impact of drug interactions and genetic polymorphisms on cytochrome P450 2C9 substrate exposure.

AC Castellan, M Tod, F Gueyffier, M Audars… - Clinical …, 2013 - europepmc.org
Methods We created two models. The genetic model was designed to predict the impact of
CYP2C9 polymorphisms on drug exposure. It links the area under the concentration-time …