Discovery and development of extreme selective inhibitors of the ITD and D835Y mutant FLT3 kinases

F Baska, A Sipos, Z Őrfi, Z Nemes, J Dobos… - European Journal of …, 2019 - Elsevier
Aberrant activation of FMS-like tyrosine receptor kinase 3 (FLT3) is implicated in the
pathogenesis of acute myeloid leukemia (AML) in 20–30% of patients. In this study we …

[PDF][PDF] Discovery and development of extreme selective inhibitors of the ITD and D835Y mutant FLT3 kinases

F Baska, A Sipos, Z Orfi, Z Nemes, J Dobos… - European Journal of …, 2019 - semmelweis.hu
abstract Aberrant activation of FMS-like tyrosine receptor kinase 3 (FLT3) is implicated in the
pathogenesis of acute myeloid leukemia (AML) in 20e30% of patients. In this study we …

Discovery and development of extreme selective inhibitors of the ITD and D835Y mutant FLT3 kinases.

F Baska, A Sipos, Z Őrfi, Z Nemes, J Dobos… - European Journal of …, 2019 - europepmc.org
Aberrant activation of FMS-like tyrosine receptor kinase 3 (FLT3) is implicated in the
pathogenesis of acute myeloid leukemia (AML) in 20-30% of patients. In this study we …

Discovery and development of extreme selective inhibitors of the ITD and D835Y mutant FLT3 kinases

F Baska, A Sipos, Z Örfi, Z Nemes, J Dobos… - EUROPEAN …, 2019 - pure.mpg.de
Aberrant activation of FMS-like tyrosine receptor kinase 3 (FLT3) is implicated in the
pathogenesis of acute myeloid leukemia (AML) in 20-30% of patients. In this study we …

Discovery and development of extreme selective inhibitors of the ITD and D835Y mutant FLT3 kinases

F Baska, A Sipos, Z Őrfi, Z Nemes… - European journal …, 2019 - pubmed.ncbi.nlm.nih.gov
Aberrant activation of FMS-like tyrosine receptor kinase 3 (FLT3) is implicated in the
pathogenesis of acute myeloid leukemia (AML) in 20-30% of patients. In this study we …