Chromatin accessibility dynamics in a model of human forebrain development

AE Trevino, N Sinnott-Armstrong, J Andersen, SJ Yoon… - Science, 2020 - science.org
INTRODUCTION The cerebral cortex is responsible for higher-order functions in the nervous
system and has undergone substantial expansion in size in primates. The development of …

Chromatin accessibility dynamics in a model of human forebrain development

AE Trevino, JA Sinnott-Armstrong, SJ Yoon, N Huber… - Science, 2020 - cir.nii.ac.jp
抄録< jats: title> Organoids recapitulate brain development</jats: title>< jats: p> Gene
expression changes and their control by accessible chromatin in the human brain during …

[HTML][HTML] Chromatin accessibility dynamics in a model of human forebrain development

AE Trevino, N Sinnott-Armstrong, J Andersen… - Science (New York …, 2020 - ncbi.nlm.nih.gov
RESULTS: We used three-dimensional (3D) directed differentiation of human pluripotent
stem cells into dorsal and ventral forebrain domains and applied the assay for transposase …

Chromatin accessibility dynamics in a model of human forebrain development

AE Trevino, N Sinnott-Armstrong… - … (New York, NY), 2020 - pubmed.ncbi.nlm.nih.gov
Forebrain development is characterized by highly synchronized cellular processes, which, if
perturbed, can cause disease. To chart the regulatory activity underlying these events, we …

Chromatin accessibility dynamics in a model of human forebrain development

AE Trevino, JA Sinnott-Armstrong, SJ Yoon, N Huber… - paper.sciencenet.cn
Forebrain development is characterized by highly synchronized cellular processes, which, if
perturbed, can cause disease. To chart the regulatory activity underlying these events, we …

Chromatin accessibility dynamics in a model of human forebrain development.

AE Trevino, N Sinnott-Armstrong, J Andersen… - Science (New York …, 2020 - europepmc.org
RESULTS: We used three-dimensional (3D) directed differentiation of human pluripotent
stem cells into dorsal and ventral forebrain domains and applied the assay for transposase …