P Fanlo, B del Carmelo Gracia-Tello… - JAMA Network …, 2023 - jamanetwork.com
… Meaning This study did not find evidence of effectiveness of anakinra vs the standard of … with severe COVID-19 pneumonia, and future research should assess anakinra in patients with …
EJ Kooistra, NJB Waalders, M Kox… - The Lancet …, 2020 - thelancet.com
… (suppression of C-reactive protein or fever) as important considerations. The use of … deci sion making at the cusp of the COVID-19 pandemic. Several ongoing clinicaltrials will follow …
T Huet, H Beaussier, O Voisin… - The Lancet …, 2020 - thelancet.com
… with COVID-19. We aimed to assess the off-label use of anakinra in patients who were admitted to hospital for severe forms of … A real-time dashboard of clinicaltrials for COVID-19. …
EJ Kooistra, NJB Waalders, I Grondman, NAF Janssen… - Critical care, 2020 - Springer
… In the present study, the effects of anakinra in critically ill COVID-19 patients with clinical … These issues might have confounded the clinical outcome results demonstrated in these …
… or completed clinicaltrials on the use of anakinra in COVID-19 … Overall, 6 ongoing trials were registered in the clinicaltrials.gov … Anakinra did not result in any critical safety issues when …
… anakinra may improve the patient's situation, and in this study, we … efficacy of anakinra in patients diagnosed with COVID-19. … As an importantconsideration to our study, we administered …
K Dahms, A Mikolajewska, K Ansems… - … of medical research, 2023 - Springer
… However, the role of Anakinra in COVID-19 remains unanswered, especially in patients … and effects of Anakinra compared to placebo or standard care alone on clinical outcomes in …
… or laboratory signs of hyperinflammation, or both, or in the context of clinicaltrials, in an … an important role in COVID-19 pathophysiology. We aimed to investigate the effect of anakinra …
… not observe a beneficial effect of anakinra in critically ill patients with COVID-19. Previous studies and a recent meta-analysis provided a rationale for the use of anakinra in COVID-19. …