… HCV RNA 24 weeks after completion of treatment. This is … after completion of treatment
seems to be highly predictive of a sustained virologic response at 24 weeks and is now accepted …

… approved for the treatment of HIV infections: zidovudine (AZT), didanosine (ddI), zalcitabine
(ddC), stavudine (d4T), lamivudine (3TC), abacavir (ABC) and emtricitabine ((−)FTC) (Fig. 10…

… NRTIs constitute a group of anti-HIV-1 drugs that were approved for the first time by the US
… Therefore, we should predict new drug-resistance problems with antiretroviral drugs in the …

… an overview of his contributions to eight approved nucleos(t)ide drugs: (i) three adenosine
… by our team member who received the antiviral drugs contributed by Prof. Erik De Clercq. …

… of action of approved and investigational drugs for HIV and HCV, … of antiviral drugs — known
as highly active antiretroviral … , 22 years after the inhibitory effects of the first anti-HIV drug, …

… -function relationships of domains within the polymerase gene (50). The academic interests
in … Since HSV pol is the ultimate target for the present clinically approved antiviral drugs ACV …

… HSV, VZV, and CMV, and are Food and Drug Administration (FDA)-approved for CMV
infection, for which antiviral potency outweighs the increased toxicity as compared with acyclovir. …

… very successfully in the optimization of many recently approved agents, we are still able to
identify … ) approved as drugs in this 39-year time frame, though there is also one drug that was …

… Integrase inhibitors (INIs) are the latest drug class developed for the treatment of HIV infection.
Raltegravir (RAL) was the first drug approved within this family. Trials involving RAL have …

… After approval and marketing of the drug, phase IV may be initiated to follow up on … approved
against FLUAV in Japan; cidofovir is an injectable antiviral medication used as a treatment …