… links aging to genetic and epigenetic alterations. Given the reversible nature of epigenetic
mechanisms, these pathways provide promising avenues for therapeutics against age-related …

… our knowledge in regards to epigenetic mechanisms underlying human longevity as well
as environmental cues that may influence these mechanisms. Further studies should continue …

… are being identified that have a positive effect on longevity. The gerontogenes are classified
as … genetic and epigenetic mechanisms that are involved in regulation of longevity are highly …

… For example, imprinted genes, a subset of mammalian genes that is monoallelically
expressed in a parent-of-origin manner due to epigenetic mechanisms that confer a parent-specific …

Here we summarize the latest data on genetic and epigenetic contributions to human aging
and longevity. Whereas environmental and lifestyle factors are important at younger ages, …

… In line with this, the general aim of this Review is to highlight how epigenetic mechanisms
are involved in ageing and longevity. Epigenetic alterations are considered one of the …

… Epigenetic mechanisms have been established to play a major role in aging at both
cellular and organism level [48,49]. In addition to DNA methylation, one of the well-characterized …

… overexpressed or mutated increase the lifespan by controlling aging and longevity [40]. On
the other hand, these age-dependent alterations produce an increased genomic instability, a …

… In this succinct review of aging and longevity we tried to summarize recent advance in this
area, avoiding lengthy discussions and presentation of large amount of data accumulated …

… longevity. In the current study, we will aim to discuss the role of epigenomic mechanisms in
aging … Moreover, epigenetic mechanisms on DNA can influence transcription, replication, and …