… -19. Here, we discuss the major inflammatory pathways in the pathogenesis of COVID-19, …
as well as existing and potential interventions targeting these cytokines or related signaling …

… These mechanisms are concordant with observed clinical markers in COVID-19, including
high expression of inflammatory … pathway suggests multiple points of investigation for potential …

… molecular mechanisms involved in COVID-19, which are initiated with ACE2 deficiency,
ADAM17 activation, and followed by the induction of pro-inflammatory pathways. In COVID-19 …

… COVID-19 and related pathogenic mechanisms, a deep appreciation of the inflammatory
mechanisms … therapeutic interventions reasonable choices to avoid disease exacerbation. It …

… of COVID-19, the therapeutic targets and interventions of … -2 and the tremendous
inflammatory/immune response to the … be potential inhibitors of type I IFN pathway. Moreover, a …

… features of COVID-19, especially the CS; its mechanism of … COVID-19 cases, which represents
a potential intervention … inflammatory pathways such as NF-κB and MAPK pathways to …

… and the synergic inflammatory cytokine IL-6 to manage COVID-19 patients, particularly those
… storm mechanisms in this disease could help to reveal possible therapeutic interventions. …

… in COVID-19 therapeutic interventions [150,151]. Inhibition of the JAK pathway represses the
… the JAK/STAT pathway is also considered as an effective therapeutic method to control the …

… shared mechanisms and differences between COVID-19 and … trials testing anti-inflammatory
therapies and of the data … COVID-19, especially by inhibiting the interleukin-6 pathway. …

… in the control of inflammation. The same authors also reveal an intriguing mechanism at the
… , and “non-canonical pathways” if other intracellular pathways are activated (eg the planer …