… diseases. Specifically, the first part of the review article will focus on the … neuronal cells’
rearrangements during aging in response to changes in metabolism and oxidative stress, while …

… metabolic dysfunction in the “normal” ageing brain is distributed in a random fashion, while
in neurodegenerative disorders… result in excitotoxic neuronal cell death, while in stark contrast…

… neurodegenerative diseases, particularly Alzheimer's … rearrangement of the neuronal
metabolic state reduces … Considering neuronal development, a metabolic switch from oxidative …

… of aging, along with the pathogenesis of age-related … normal protein metabolism often cause
neuronal cell death and … affecting protein expression and rearrangements of mtDNA. The …

… [Citation9] Peroxyl radicals ( RO 2 ⋅ ) can be rearranged via a … Chronic effects of these
mediators may result in neuronal cell … population of neurons that has high metabolic activity in AD …

… These findings, and the intrinsic potential for the oxidative metabolism of dopamine to … of
aberrant neuronal cell cycle reentry in progressive human neurodegenerative diseases, we …

… , neuronal mitochondria are capable of oxidizing ketone … Single-cell transcriptomic analysis
identified the decreased … brain aging, prevalent across neurons and non-neuronal cell types […

… neuronal RNA oxidation compared to normal aging have been described in neurodegenerative
disorders including Alzheimer disease… ROS metabolism, aging, and neurodegeneration, …

… leads to the damage to nerve cell as they are metabolically very … radical dot ) can be
rearranged via a cyclisation reaction to … Various metabolic and neurodegenerative diseases have …

… high levels of oxidative metabolism that affects cell structure, leading to neuronal damage. …
prevalence of T2DM and associated disorders such as MetS among the aging population. …